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afzole 150mg tablet allopathy (Fluconazole (150mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
afzole 150mg tablet allopathy (Fluconazole (150mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Mclain Laboratories. Contains Fluconazole (150mg).

Afzole 150mg Tablet - Uses, Price, Side Effects

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Fluconazole (150mg) (Click to see all medicines with same salt)
🏭 Mclain Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is afzole 150mg tablet used for?

Afzole 150mg Tablet contains Fluconazole, an antifungal medication used to treat fungal infections such as vaginal candidiasis, oral thrush, and systemic fungal infections like cryptococcal meningitis. It works by inhibiting the growth of fungi. Take one tablet as a single dose for vaginal candidiasis, or as directed by your doctor for other infections.

  • Generic Name: Fluconazole
  • Manufacturer: Mclain Laboratories
  • Medicine Form: Allopathy
  • Pregnancy Category: D

🇮🇳 afzole 150mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

afzole 150mg tablet का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Fluconazole (150mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Fluconazole
Brand NameAF 150 Tablet DT
ManufacturerMclain Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFungal ergosterol synthesis inhibitor
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; bioavailability >90%
DistributionWidely distributed into body tissues and fluids, including CSF
Protein Binding11-12%
MetabolismHepatic metabolism via CYP2C9 and CYP3A4
Half-Life30 hours (range 20-50 hours)
ExcretionPrimarily renal (80% unchanged)
Bioavailability>90%
Onset of ActionRapid; therapeutic levels achieved within 1-2 hours
Peak Plasma Time1-2 hours
Duration of Action24 hours

Pharmacodynamics

Mechanism of ActionInhibits fungal cytochrome P450 14α-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis
Target ReceptorFungal CYP51 (lanosterol 14α-demethylase)
Pharmacodynamic EffectsFungistatic activity against Candida spp., Cryptococcus neoformans, and other fungi

📅 When to take afzole 150mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

💡 How and when to take afzole 150mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light and moisture

⚙️ How afzole 150mg tablet Works

Inhibits fungal cytochrome P450 14α-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis

1 Fluconazole enters fungal cell via diffusion
⬇️
2 Binds to fungal cytochrome P450 14α-demethylase (CYP51)
⬇️
3 Inhibits demethylation of lanosterol to ergosterol
⬇️
4 Depletes ergosterol in fungal cell membrane
⬇️
5 Accumulates toxic 14α-methyl sterols
⬇️
6 Disrupts membrane integrity and function
⬇️
7 Leads to fungal cell growth inhibition and death

💊 afzole 150mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Vaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, prophylaxis in immunocompromised patients

Off-label uses: Coccidioidomycosis, histoplasmosis, blastomycosis, dermatophytosis, onychomycosis

⚠️ What are the side effects of afzole 150mg tablet?

✅ Common Side Effects

  • Headache
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Dizziness
  • Rash

🚨 Serious Side Effects

  • Hepatotoxicity
  • QT prolongation
  • Torsades de pointes
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Exfoliative dermatitis

⚠️ Rare Side Effects

  • Alopecia
  • Seizures
  • Thrombocytopenia
  • Leukopenia
  • Agranulocytosis
  • Hypertriglyceridemia
  • Hypokalemia

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for afzole 150mg tablet

View All

Alternative brands with exact same active ingredient and strength (Fluconazole (150mg)):

  1. angloflu 150mg tablet
    Anglo-French Drugs & Industries Ltd₹4.18💰 97% CHEAPER
  2. fluent 150mg tablet
    Torrent Pharmaceuticals Ltd₹4.62💰 96.7% CHEAPER
  3. markzole 150mg tablet
    Glenmark Pharmaceuticals Ltd₹4.87💰 96.5% CHEAPER
  4. flucess 150mg tablet
    Novartis India Ltd₹5.00💰 96.4% CHEAPER
  5. flumed 150mg tablet
    Zydus Healthcare Limited₹5.00💰 96.4% CHEAPER
  6. fluzant 150mg tablet
    Elder Pharmaceuticals Ltd₹5.00💰 96.4% CHEAPER
  7. funaz 150mg tablet
    Wockhardt Ltd₹5.00💰 96.4% CHEAPER
  8. nucan 150mg tablet
    Medley Pharmaceuticals₹5.00💰 96.4% CHEAPER
  9. cancap 150 mg tablet
    Ind Swift Laboratories Ltd₹5.19💰 96.3% CHEAPER
  10. davaindia fluconazole 150mg tablet
    Davaindia Generic Pharmacy₹5.63💰 96% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Cisapride Major Risk of serious cardiac arrhythmias
Sulfonylureas Moderate Increased hypoglycemic effect

🚨 Major Interactions

  • Warfarin
  • Phenytoin
  • Sulfonylureas
  • Cisapride
  • Terfenadine
  • Astemizole
  • Rifampin
  • Rifabutin
  • Tacrolimus
  • Sirolimus
  • Alfentanil
  • Benzodiazepines (midazolam, triazolam)
  • Calcium channel blockers (nifedipine, verapamil)
  • HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
  • Losartan
  • Methadone
  • NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
  • Oral contraceptives
  • Pimozide
  • Quinidine
  • Tolbutamide
  • Warfarin
  • Zidovudine

⚡ Moderate Interactions

  • Cyclosporine
  • Theophylline
  • Hydrochlorothiazide
  • Phenytoin
  • Rifampin
  • Rifabutin
  • Tacrolimus
  • Sirolimus
  • Alfentanil
  • Benzodiazepines (midazolam, triazolam)
  • Calcium channel blockers (nifedipine, verapamil)
  • HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
  • Losartan
  • Methadone
  • NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
  • Oral contraceptives
  • Pimozide
  • Quinidine
  • Tolbutamide
  • Warfarin
  • Zidovudine

ℹ️ Minor Interactions

  • Cimetidine
  • Antacids
  • Sucralfate
  • Didanosine
  • Ritonavir
  • Saquinavir
  • Zidovudine

🍽️ Food Interactions

No significant food interactions; absorption not affected by food

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category D

🚫 Contraindications

Hypersensitivity to fluconazole or azoles; concomitant use with terfenadine, astemizole, cisapride, pimozide, quinidine

📊 Monitoring Parameters

Liver function tests, renal function, signs of hepatotoxicity, QT interval if risk factors

🤱 Lactation Safety

Excreted in breast milk; use with caution

💊 Overdose Management

Symptomatic and supportive; hemodialysis may enhance elimination

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

🛑 Myths vs. Facts about afzole 150mg tablet

  • Myth: Generic substitutes of afzole 150mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Fluconazole (150mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of afzole 150mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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Read real stories and discussions from our patient community regarding similar health conditions.

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Bhai onion juice ka koi genuine result hai ya bas social media ka hype hai? Mene kal raat pehli baar lagaya, aankhon mein itna jal raha tha ki lag raha tha koi ro raha hai 😭. 2 hafte se minoxidil use kar raha hu, par side effects ka dar lagta hai. Koi batao, onion juice actually hair regrowth karta hai ya bas basel aur aloe wale influencers ka commission ka scene hai? Mera friend kehta hai "ye sab fake hai, bas bakwas hai", lekin main desperate hu. Hairline pe patches dekh ke dil dukhta hai. College mein "takla" bol ke chidhate hain, ab toh cap pehne bina bahar nikalna mushkil ho gaya hai. Kya koi genuine experience share kar sakta hai? Pls bina sarcasm ke, main seriously try kar raha hu.

Lower Back Pain Relief: Best Sleep Positions & Stretches

Lower back pain and sciatica are among the most common complaints I see in my clinic, especially among Indian patients who spend long hours sitting at desks, driving, or performing household chores like squatting on the floor. The sharp, shooting pain that travels down your leg—often called sciatica—can make even simple movements feel impossible. But the good news is that your sleeping position and a few targeted stretches can offer instant relief. Why Does Your Back Hurt? Common Causes in India In our daily lives, poor posture while sitting on the floor, lifting heavy objects incorrectly, or sleeping on an unsupportive mattress can strain the lumbar spine. Sciatica occurs when the sciatic nerve is compressed, often by a herniated disc or tight piriformis muscle. This nerve runs from your lower back down to your toes, so pain can radiate through your buttocks, thighs, and calves. If you’ve been ignoring that nagging ache, it’s time to take action. Best Sleeping Positions for Instant Relief Your sleep position can either aggravate or heal your back. Here are three scientifically-backed positions that reduce pressure on your spine: On your side with a pillow between your knees: This keeps your hips, pelvis, and spine aligned. Use a firm pillow to prevent your upper leg from pulling your spine out of alignment. On your back with a pillow under your knees: This flattens your lower back and reduces stress on the lumbar discs. If you have sciatica, a small rolled towel under your lower back can also help. Fetal position (on your side, knees curled toward chest): This opens up the spinal canal and reduces pressure on the sciatic nerve. Switch sides every few hours to avoid stiffness. Avoid sleeping on your stomach—it twists your neck and flattens the natural curve of your lower back, worsening pain. 5 Stretches for Instant Relief (Do These Daily) These stretches are safe for most people, but always listen to your body. Stop if you feel sharp pain. Knee-to-chest stretch: Lie on your back, pull one knee toward your chest, hold for 30 seconds, and repeat on the other side. This releases tight lower back muscles. Piriformis stretch (sciatica relief): Sit on a chair, cross your painful leg over the other knee, and gently lean forward. You’ll feel a stretch in your buttock—hold for 30 seconds. Cat-cow stretch: On all fours, arch your back like a cat, then drop your belly like a cow. Do this slowly for 1-2 minutes to improve spinal flexibility. Child’s pose: Kneel on the floor, sit back on your heels, and stretch your arms forward. This decompresses your lower back and calms your nervous system. Standing hamstring stretch: Place one heel on a low stool, keep your back straight, and lean forward. Tight hamstrings often pull on your lower back. Home Remedies and Diet Tips Inflammation is the root cause of most back pain. Include turmeric (haldi) in your diet—its curcumin acts as a natural anti-inflammatory. Drink warm ginger tea twice a day. Avoid oily, fried foods and refined sugar, which increase inflammation. Apply a hot water bottle or ice pack to the painful area for 15 minutes, 3-4 times a day. If you’re constipated, straining can worsen back pain, so eat fiber-rich foods like dal, vegetables, and whole grains. When to See a Doctor Immediately While most back pain resolves with rest and stretches, some symptoms require urgent medical care. Visit a doctor if you experience: Numbness or weakness in your legs or feet Loss of bladder or bowel control (this is a medical emergency) Pain after a fall or injury Fever or unexplained weight loss Pain that persists for more than 2 weeks despite home care Remember, your spine is the pillar of your body. Treat it with care. Start with these sleeping positions and stretches tonight—your back will thank you in the morning.

Dil Ka Silent Heart Attack: 5 Signs Kabhi Ignore Na Karein

Dil ka dard hamesha seene mein nahi hota. Bahut baar, heart attack ke silent signs aapko pata bhi nahi chalte. Main Dr. [Aapka Naam], aapko bata raha hoon wo 5 khatarnak signs jo kabhi ignore nahi karne chahiye, khaas kar auraton aur mardon mein alag alag hote hain. Mardon mein silent signs (Purushon mein) Seene mein bharipan ya dabaav: Yeh sabse common sign hai, lekin hamesha tez dard nahi hota. Kuch logon ko sirf hawa ki kami ya ghabrahat hoti hai. Baye kandhe ya baazu mein dard: Yeh dard achanak uth sakta hai aur aaram karne se bhi nahi jaata. Paseena aana: Bina kisi mehnat ke, thanda paseena aana (cold sweat) ek warning hai. Jee ghabrana ya ulti aana: Khaas kar jab aapne kuch nahi khaya ho. Sans phoolna: Seedha baithne ya lete waqt bhi saans lene mein takleef. Auraton mein silent signs (Mahilaaon mein) Thakaan jo khatam nahi hoti: Bahut si auraton ko heart attack se pehle hafton tak extreme fatigue hoti hai. Peeth, jaw ya gale mein dard: Seena nahi, lekin peeth ke upar ya jaw mein dard aata hai. Neend na aana ya achanak jaagna: Heart attack se pehle raat ko neend mein khulna common hai. Halka chakkar aana ya behoshi: Khaas kar exercise ke dauran ya baad mein. Pet ke upar ya pachas mein jalan: Gas ka dard samajh kar ignore karna sabse bada galti hai. Kyun hota hai heart attack? Heart attack tab hota hai jab dil tak jaane wali arteries mein cholesterol aur fat ka plaque jam jata hai. Yeh plaque toot kar blood clot bana leta hai, jo dil tak blood supply rok deta hai. High BP, diabetes, smoking, stress aur unhealthy diet iske main karan hain. Ghar par kya karein? (Home Remedies & Diet) Lahsun: Roz 1-2 kachi lahsun ki kaliyan khaayein. Isse blood pressure kam hota hai aur arteries saaf rehti hain. Haldi: Haldi mein curcumin hota hai jo inflammation kam karta hai. Ek glass doodh mein haldi daal kar piyein. Adrak ki chai: Adrak blood circulation improve karti hai aur cholesterol kam karti hai. Dry fruits: Akhrot, badaam aur walnut roz 5-6 khaayein. Ye heart ke liye superfood hain. Green tea: Roz 2 cup green tea piyein. Isme antioxidants hote hain jo arteries ko damage se bachate hain. Exercise: Roz 30 minute walk ya light yoga karein. Stress kam karein aur deep breathing karein. Doctor ke paas kab jaayein? Agar aapko upar diye gaye koi bhi signs dikhein, to turant doctor se milein. Deri na karein. Khaas kar agar: Seene mein dard 5-10 minute se zyada rahe. Sans phoolna ya paseena aana band na ho. Aapko diabetes ya high BP ho. Family mein heart attack ka history ho. Yaad rakhein: Heart attack ka pehla sign hamesha drama nahi hota. Kabhi kabhi ek chhoti si baat bhi bachaa sakti hai. Apne aur apne parivaar ke liye alert rahein. Astitva Health Community ke saath, aap apne dil ka khayal rakh sakte hain.

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