afocoxib 90mg tablet - Uses, Price, Side Effects & Substitutes
What is afocoxib 90mg tablet used for?
Arixib 90 Tablet (Etoricoxib) is used to treat Osteoarthritis. It contains Etoricoxib (90mg), which Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthes. Always consult your doctor before use. Take as prescribed.
- Generic Name: Etoricoxib
- Manufacturer: Glorior Biotech Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 afocoxib 90mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
afocoxib 90mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Etoricoxib (90mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Etoricoxib |
|---|---|
| Brand Name | Arixib 90 Tablet |
| Manufacturer | Glorior Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's -Selective COX-2 Inhibitors |
| Route of Administration | Oral. |
| Storage | Store at room temperature (20-25°C), protect from moisture and light. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take afocoxib 90mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from moisture and light.
⚙️ How afocoxib 90mg tablet Works
Selective inhibition of cyclooxygenase-2 (COX-2), reducing prostaglandin synthesis.
💊 afocoxib 90mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, dental pain, dysmenorrhea.
Off-label uses: Acute pain, migraine, cancer pain.
⚠️ What are the side effects of afocoxib 90mg tablet?
✅ Common Side Effects
- Headache
- Dizziness
- Diarrhea
- Dyspepsia
- Nausea
- Edema
🚨 Serious Side Effects
- GI bleeding
- Peptic ulcer
- Cardiovascular thrombotic events
- Hypertension
- Renal failure
- Hepatotoxicity
⚠️ Rare Side Effects
- Stevens-Johnson syndrome
- Anaphylaxis
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased risk of GI ulceration and bleeding |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels and toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Diuretics | Major | Reduced diuretic effect and increased risk of renal impairment |
| Fluconazole | Moderate | Increased etoricoxib levels |
| Ketoconazole | Moderate | Increased etoricoxib levels |
| Corticosteroids | Moderate | Increased risk of GI ulceration |
| SSRIs | Moderate | Increased risk of bleeding |
| Antacids | Minor | Slight decrease in absorption |
| Cimetidine | Minor | No significant interaction |
🚨 Major Interactions
- Warfarin
- Aspirin
- Methotrexate
- Lithium
- ACE inhibitors
- Diuretics
⚡ Moderate Interactions
- CYP2C9 inhibitors (e.g., fluconazole)
- CYP3A4 inhibitors (e.g., ketoconazole)
- Corticosteroids
- SSRIs
ℹ️ Minor Interactions
- Antacids
- Cimetidine
🍽️ Food Interactions
Food delays absorption but does not affect extent.
🍷 Alcohol Interaction
Increased risk of GI bleeding.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic impairment, severe renal impairment, pregnancy (third trimester), history of asthma, urticaria, or allergic-type reactions after taking aspirin or NSAIDs.
📊 Monitoring Parameters
Renal function, liver function, blood pressure, signs of GI bleeding, cardiovascular events.
🤱 Lactation Safety
Not recommended; excreted in breast milk.
💊 Overdose Management
Symptomatic and supportive care; no specific antidote; consider gastric lavage if recent ingestion.
⏰ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose.
🛑 Myths vs. Facts about afocoxib 90mg tablet
- Myth: Generic substitutes of afocoxib 90mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Etoricoxib (90mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of afocoxib 90mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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