afixim 50mg dry syrup - Cefixime (50mg/5ml) medicine

Afixim 50mg Dry Syrup - Uses, Price, Side Effects

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๐Ÿญ Acto Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is afixim 50mg dry syrup used for?

Afixim 50mg Dry Syrup contains Cefixime, a cephalosporin antibiotic that treats bacterial infections like respiratory tract infections, otitis media, and urinary tract infections. It works by stopping bacterial cell wall synthesis, killing the bacteria. Use as prescribed.

  • Generic Name: Cefixime
  • Manufacturer: Acto Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š afixim 50mg dry syrup Uses & Benefits

Treatment of respiratory tract infections, urinary tract infections, otitis media, pharyngitis, tonsillitis, gonorrhea.

Off-label uses: Lyme disease, typhoid fever, prophylaxis of bacterial endocarditis.

๐Ÿ“‹ Drug Information

Generic Name(s)Cefixime
Brand NameAbixim
ManufacturerActo Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; oral bioavailability approximately 40-50%.
DistributionDistributes widely into body tissues and fluids; crosses placenta; small amounts enter breast milk.
Protein BindingApproximately 65% bound to plasma proteins.
MetabolismPartially metabolized in the liver; primarily excreted unchanged.
Half-Life3-4 hours (prolonged in renal impairment).
ExcretionPrimarily excreted unchanged in urine via glomerular filtration and tubular secretion; also in bile.
Bioavailability40-50%
Onset of ActionRapid; peak serum concentrations within 2-6 hours.
Peak Plasma Time2-6 hours
Duration of ActionApproximately 12-24 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidation and disrupting cell wall integrity.

Mechanism Steps

1Cefixime binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase activity, preventing cross-linking of peptidoglycan chains.
3Disrupts cell wall synthesis, leading to osmotic instability and bacterial lysis.

๐Ÿ’ก How to Take afixim 50mg dry syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of afixim 50mg dry syrup

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe hypersensitivity reactions (anaphylaxis)
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Thrombocytopenia
  • Interstitial nephritis
  • Hepatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Probenecid Moderate Increased cefixime concentration
Live typhoid vaccine Moderate Reduced vaccine efficacy

๐Ÿšจ Major Interactions

  • Warfarin
  • Probenecid
  • Live typhoid vaccine

โšก Moderate Interactions

  • BCG vaccine
  • Cholera vaccine

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

Food delays absorption but does not significantly reduce extent; may be taken with or without food.

๐Ÿท Alcohol Interaction

No known interaction; however, alcohol may increase risk of gastrointestinal side effects.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to cefixime or other cephalosporins; severe renal impairment (CrCl < 60 mL/min) without dose adjustment.

๐Ÿ“Š Monitoring Parameters

Renal function, signs of hypersensitivity, prothrombin time if on warfarin.

๐Ÿคฑ Lactation Safety

Excreted in small amounts; considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for afixim 50mg dry syrup

View All

Alternative brands with exact same active ingredient (Cefixime (50mg/5ml)):

Medical Note: Always consult your doctor before switching medications.

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