afcon 150mg tablet - Uses, Price, Side Effects & Substitutes
What is afcon 150mg tablet used for?
AF 150 Tablet DT (Fluconazole) is used to treat Vaginal candidiasis. It contains Fluconazole (150mg), which Inhibits fungal cytochrome P450 14α-demethylase, preventing conversion of lanos. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluconazole
- Manufacturer: AS Lifesciences
- Medicine Form: Allopathy
- Pregnancy Category: D
🇮🇳 afcon 150mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
afcon 150mg tablet का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Fluconazole (150mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Fluconazole |
|---|---|
| Brand Name | AF 150 Tablet DT |
| Manufacturer | AS Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25°C (68-77°F); protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take afcon 150mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F); protect from light and moisture
⚙️ How afcon 150mg tablet Works
Inhibits fungal cytochrome P450 14α-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis
💊 afcon 150mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Vaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, prophylaxis in immunocompromised patients
Off-label uses: Coccidioidomycosis, histoplasmosis, blastomycosis, dermatophytosis, onychomycosis
⚠️ What are the side effects of afcon 150mg tablet?
✅ Common Side Effects
- Headache
- Nausea
- Abdominal pain
- Diarrhea
- Dizziness
- Rash
🚨 Serious Side Effects
- Hepatotoxicity
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
- Anaphylaxis
- Exfoliative dermatitis
⚠️ Rare Side Effects
- Alopecia
- Seizures
- Thrombocytopenia
- Leukopenia
- Agranulocytosis
- Hypertriglyceridemia
- Hypokalemia
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Phenytoin | Major | Increased phenytoin levels, toxicity |
| Sulfonylureas | Major | Hypoglycemia |
| Cisapride | Major | QT prolongation, arrhythmias |
| Terfenadine | Major | QT prolongation, arrhythmias |
| Astemizole | Major | QT prolongation, arrhythmias |
| Rifampin | Major | Decreased fluconazole efficacy |
| Rifabutin | Major | Increased rifabutin levels, uveitis |
| Tacrolimus | Major | Increased tacrolimus levels, nephrotoxicity |
| Sirolimus | Major | Increased sirolimus levels |
| Alfentanil | Major | Increased alfentanil levels, respiratory depression |
| Midazolam | Major | Increased midazolam levels, sedation |
| Triazolam | Major | Increased triazolam levels, sedation |
| Nifedipine | Major | Increased nifedipine levels, hypotension |
| Verapamil | Major | Increased verapamil levels, bradycardia |
| Atorvastatin | Major | Increased statin levels, myopathy |
| Simvastatin | Major | Increased statin levels, myopathy |
| Losartan | Major | Decreased losartan efficacy |
| Methadone | Major | Increased methadone levels, QT prolongation |
| Celecoxib | Major | Increased celecoxib levels |
| Flurbiprofen | Major | Increased flurbiprofen levels |
| Naproxen | Major | Increased naproxen levels |
| Ibuprofen | Major | Increased ibuprofen levels |
| Oral contraceptives | Major | Decreased contraceptive efficacy |
| Pimozide | Major | QT prolongation, arrhythmias |
| Quinidine | Major | QT prolongation, arrhythmias |
| Tolbutamide | Major | Hypoglycemia |
| Zidovudine | Major | Increased zidovudine levels |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Theophylline | Moderate | Increased theophylline levels, toxicity |
| Hydrochlorothiazide | Moderate | Increased fluconazole levels |
| Cimetidine | Minor | Decreased fluconazole absorption |
| Antacids | Minor | Decreased fluconazole absorption |
| Sucralfate | Minor | Decreased fluconazole absorption |
| Didanosine | Minor | Decreased fluconazole absorption |
| Ritonavir | Minor | Increased fluconazole levels |
| Saquinavir | Minor | Increased saquinavir levels |
🚨 Major Interactions
- Warfarin
- Phenytoin
- Sulfonylureas
- Cisapride
- Terfenadine
- Astemizole
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
⚡ Moderate Interactions
- Cyclosporine
- Theophylline
- Hydrochlorothiazide
- Phenytoin
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
ℹ️ Minor Interactions
- Cimetidine
- Antacids
- Sucralfate
- Didanosine
- Ritonavir
- Saquinavir
- Zidovudine
🍽️ Food Interactions
No significant food interactions; absorption not affected by food
🍷 Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to fluconazole or azoles; concomitant use with terfenadine, astemizole, cisapride, pimozide, quinidine
📊 Monitoring Parameters
Liver function tests, renal function, signs of hepatotoxicity, QT interval if risk factors
🤱 Lactation Safety
Excreted in breast milk; use with caution
💊 Overdose Management
Symptomatic and supportive; hemodialysis may enhance elimination
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
🛑 Myths vs. Facts about afcon 150mg tablet
- Myth: Generic substitutes of afcon 150mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Fluconazole (150mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of afcon 150mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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