adapure gel - Uses, Price, Side Effects & Substitutes
What is adapure gel used for?
Ab-Next Gel (Adapalene + Benzoyl Peroxide) is used to treat DERMA. It contains Adapalene (0.1% w/w) + Benzoyl Peroxide (2.5% w/w), which Adapalene binds to retinoic acid receptors (RAR) to normalize follicular keratin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Adapalene + Benzoyl Peroxide
- Manufacturer: Iceberg Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ adapure gel Uses & Benefits
Acne vulgaris (comedonal, inflammatory)
Off-label uses: Keratosis pilaris, Photoaging
๐ Drug Information
| Generic Name(s) | Adapalene + Benzoyl Peroxide |
| Brand Name | Ab-Next Gel |
| Manufacturer | Iceberg Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Retinoid + Antimicrobial |
| Route of Administration | Topical |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Adapalene binds to retinoic acid receptors (RAR) to normalize follicular keratinization; benzoyl peroxide releases free radicals to kill Propionibacterium acnes and reduce comedones
Mechanism Steps
๐ก How to Take adapure gel
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of adapure gel
โ Common Side Effects
- Dryness
- Peeling
- Erythema
- Burning
- Stinging
๐จ Serious Side Effects
- Severe allergic reaction
- Angioedema
โ ๏ธ Rare Side Effects
- Hyperpigmentation
- Hypopigmentation
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Other topical retinoids | Major | Increased skin irritation and peeling |
| Sulfur | Major | Enhanced drying and irritation |
| Resorcinol | Major | Increased skin sensitivity |
| Salicylic acid | Major | Additive irritation |
| Topical clindamycin | Moderate | Possible additive irritation |
| Topical erythromycin | Moderate | Possible additive irritation |
| Other benzoyl peroxide products | Moderate | Increased irritation and dryness |
| Cosmetics with alcohol | Minor | Mild irritation |
๐จ Major Interactions
- Other topical retinoids
- Sulfur
- Resorcinol
- Salicylic acid
โก Moderate Interactions
- Topical antibiotics (clindamycin, erythromycin)
- Benzoyl peroxide-containing products
โน๏ธ Minor Interactions
- Cosmetics with alcohol or astringents
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
May increase skin irritation; avoid excessive use
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to adapalene, benzoyl peroxide, or any component; eczema; sunburn
๐ Monitoring Parameters
Skin irritation, dryness, peeling; improvement in acne lesions
๐คฑ Lactation Safety
Not recommended; avoid application to breast area
๐ Overdose Management
Excessive topical application may cause severe irritation; treat symptomatically; accidental ingestion: supportive care
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose; do not double