adalipca 40mg injection allopathy (Adalimumab (40mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
adalipca 40mg injection allopathy (Adalimumab (40mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Ipca Laboratories Ltd. Contains Adalimumab (40mg).

adalipca 40mg injection - Uses, Price, Side Effects & Substitutes

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Adalimumab (40mg) (Click to see all medicines with same salt)
🏭 Ipca Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is adalipca 40mg injection used for?

Adalipca 40mg Injection (Adalimumab) is used to treat Rheumatoid arthritis. It contains Adalimumab (40mg), which Adalimumab is a recombinant human IgG1 monoclonal antibody that binds specifical. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Adalimumab
  • Manufacturer: Ipca Laboratories Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 adalipca 40mg injection के बारे में संक्षिप्त जानकारी (Hindi Summary)

adalipca 40mg injection का उपयोग मुख्य रूप से anti neoplastics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Adalimumab (40mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

📋 Drug Information

Generic Name(s)Adalimumab
Brand NameAdalipca 40mg Injection
ManufacturerIpca Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassDisease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics
Route of AdministrationSubcutaneous injection.
StorageStore at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSubcutaneous administration results in slow absorption with peak serum concentrations reached approximately 5 days after a single dose.
DistributionDistributes into the vascular space and extravascular tissues; volume of distribution is about 4.7-6 L.
Protein BindingBinds to TNF-alpha; no specific protein binding data available.
MetabolismDegraded into small peptides and amino acids via proteolytic catabolism.
Half-LifeApproximately 10-20 days (mean 14 days).
ExcretionNot excreted renally; eliminated via reticuloendothelial system.
BioavailabilityApproximately 64% after subcutaneous injection.
Onset of ActionClinical response may be seen within 1-2 weeks.
Peak Plasma Time5 days (131 hours) after a single subcutaneous dose.
Duration of ActionSustained effect due to long half-life; dosing every 2 weeks.

Pharmacodynamics

Mechanism of ActionAdalimumab is a recombinant human IgG1 monoclonal antibody that binds specifically to human tumor necrosis factor-alpha (TNF-alpha) and neutralizes its biological activity by blocking its interaction with p55 and p75 cell surface TNF receptors.
Target ReceptorTNF-alpha (soluble and membrane-bound).
Pharmacodynamic EffectsReduces inflammation, inhibits cytokine production, decreases adhesion molecule expression, and induces apoptosis of TNF-expressing cells.

💡 How and when to take adalipca 40mg injection?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.

⚙️ How adalipca 40mg injection Works

Adalimumab is a recombinant human IgG1 monoclonal antibody that binds specifically to human tumor necrosis factor-alpha (TNF-alpha) and neutralizes its biological activity by blocking its interaction with p55 and p75 cell surface TNF receptors.

1 Adalimumab binds to soluble and membrane-bound TNF-alpha with high affinity.
⬇️
2 Neutralizes TNF-alpha activity by preventing its interaction with TNFR1 and TNFR2 receptors.
⬇️
3 Reduces TNF-alpha-mediated pro-inflammatory cytokine production (e.g., IL-1, IL-6).
⬇️
4 Decreases expression of adhesion molecules (e.g., E-selectin, ICAM-1) on endothelial cells.
⬇️
5 Induces apoptosis of TNF-expressing cells via reverse signaling.
⬇️
6 Modulates immune cell activation and migration, reducing inflammation.

💊 adalipca 40mg injection Uses in Hindi (Ke Fayde), Benefits & Indications

Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, uveitis.

Off-label uses: Behçet's disease, Sarcoidosis, Pyoderma gangrenosum, Graft-versus-host disease

⚠️ What are the side effects of adalipca 40mg injection?

✅ Common Side Effects

  • Injection site reactions (erythema, itching, pain)
  • Upper respiratory infections
  • Headache
  • Nausea
  • Rash

🚨 Serious Side Effects

  • Serious infections (tuberculosis, invasive fungal infections)
  • Malignancies (lymphoma)
  • Demyelinating disorders
  • Heart failure exacerbation
  • Lupus-like syndrome

⚠️ Rare Side Effects

  • Aplastic anemia
  • Stevens-Johnson syndrome
  • Hepatitis B reactivation
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Abatacept Major Increased risk of serious infections
Anakinra Major Increased risk of serious infections and neutropenia
Live vaccines Major Risk of disseminated infection
Tocilizumab Major Increased immunosuppression and infection risk
Cyclosporine Moderate Reduced efficacy of cyclosporine
Warfarin Moderate Altered anticoagulant effect
Theophylline Moderate Increased theophylline levels
ACE inhibitors Minor Possible decreased efficacy of ACE inhibitors
Beta-blockers Minor Possible decreased efficacy of beta-blockers

🚨 Major Interactions

  • Abatacept
  • Anakinra
  • Live vaccines
  • Tocilizumab

⚡ Moderate Interactions

  • Cyclosporine
  • Warfarin
  • Theophylline

ℹ️ Minor Interactions

  • ACE inhibitors
  • Beta-blockers

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No specific interaction; caution with liver function.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to adalimumab or any component; active infections including tuberculosis; moderate to severe heart failure (NYHA class III/IV).

📊 Monitoring Parameters

Monitor for signs of infection, tuberculosis screening before and during therapy, CBC, liver function tests, and injection site reactions.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

No specific antidote; monitor for adverse effects and provide supportive care.

⏰ Missed Dose

If a dose is missed, administer as soon as remembered; then resume regular schedule. Do not double dose.

🛑 Myths vs. Facts about adalipca 40mg injection

  • Myth: Generic substitutes of adalipca 40mg injection are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Adalimumab (40mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of adalipca 40mg injection can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Biologics ka kharcha 30k mahina! Koi sasta option hai ya government scheme?

Arre yaar, mera dil karta hai ab bas chilla doon. Biologics le rahi hoon, Adalimumab naam hai, lekin har mahine ka kharcha 25-30 hazar se kam nahi. Pehle toh doctor ne kaha tha ki biosimilars bhi kaam karte hain, toh try kiya, lekin usse bhi 15-20 hazar lagte hain. Aur side effects toh alag se—thakaan, skin rash, aur kabhi infection ho jata hai. Mere fingers ab permanently deformed ho gaye hain. Kal hi paani ki bottle nahi pakad payi, aur mera beta mujhe dekh ke ro pada. Uska college fees bhi baaki hai, aur main sochti hoon ki yeh dawai le ya ghar ka kharcha. Mera pati retired hain, toh unki pension se toh nahi ho paata. Mujhe koi batao, kya koi government scheme hai jo biologics ka cost cover kare? Ya koi cheaper alternative hai jo kaam kare? Main Mumbai mein rehti hoon, toh local hospital se bhi baat ki, lekin woh bhi 50% discount dete hain, utna bhi bahut hai. Thoda sa guidance chahiye, please.

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