Acvom 10mg/20mg Tablet - Uses, Price, Side Effects
What is acvom 10mg/20mg tablet used for?
Acvom 10mg/20mg Tablet is a combination of Domperidone and Omeprazole used to treat gastroesophageal reflux disease (GERD), acidity, and heartburn. Domperidone helps control nausea and vomiting by increasing stomach motility, while Omeprazole reduces stomach acid production. This dual action provides relief from symptoms like burning sensation and regurgitation.
- Generic Name: Domperidone + Omeprazole
- Manufacturer: Pharma Plus
- Medicine Form: Allopathy
- Pregnancy Category: C
🇮🇳 acvom 10mg/20mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
acvom 10mg/20mg tablet का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Domperidone (10mg) + Omeprazole (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Domperidone + Omeprazole |
|---|---|
| Brand Name | Aciloc RD 20 Tablet |
| Manufacturer | Pharma Plus |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
📅 When to take acvom 10mg/20mg tablet?
💡 How and when to take acvom 10mg/20mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture.
⚙️ How acvom 10mg/20mg tablet Works
Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.
💊 acvom 10mg/20mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.
Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.
⚠️ What are the side effects of acvom 10mg/20mg tablet?
✅ Common Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Dry mouth
🚨 Serious Side Effects
- QT prolongation
- Torsades de pointes
- Extrapyramidal symptoms
- Gynecomastia
- Hyperprolactinemia
- Interstitial nephritis
⚠️ Rare Side Effects
- Hepatotoxicity
- Anaphylaxis
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Clopidogrel | Moderate | Reduced antiplatelet effect |
| Digoxin | Moderate | Increased digoxin levels |
| Methotrexate | Major | Increased methotrexate toxicity |
🚨 Major Interactions
- Ketoconazole
- Itraconazole
- Voriconazole
- Clarithromycin
- Erythromycin
- Ritonavir
- Saquinavir
- Telithromycin
- Nefazodone
- Cobicistat
⚡ Moderate Interactions
- Warfarin
- Cilostazol
- Methotrexate
- Tacrolimus
- Fluconazole
- Cimetidine
- Digoxin
- Iron salts
- Mycophenolate mofetil
ℹ️ Minor Interactions
- Sucralfate
- Antacids
- Theophylline
- Caffeine
🍽️ Food Interactions
Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.
📊 Monitoring Parameters
ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.
🤱 Lactation Safety
Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.
💊 Overdose Management
Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.
⏰ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.
🛑 Myths vs. Facts about acvom 10mg/20mg tablet
- Myth: Generic substitutes of acvom 10mg/20mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Domperidone (10mg) + Omeprazole (20mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of acvom 10mg/20mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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