acvom 10mg/20mg tablet allopathy (Domperidone (10mg) + Omeprazole (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acvom 10mg/20mg tablet allopathy (Domperidone (10mg) + Omeprazole (20mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Pharma Plus. Contains Domperidone (10mg) + Omeprazole (20mg).

Acvom 10mg/20mg Tablet - Uses, Price, Side Effects

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🏭 Pharma Plus 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acvom 10mg/20mg tablet used for?

Acvom 10mg/20mg Tablet is a combination of Domperidone and Omeprazole used to treat gastroesophageal reflux disease (GERD), acidity, and heartburn. Domperidone helps control nausea and vomiting by increasing stomach motility, while Omeprazole reduces stomach acid production. This dual action provides relief from symptoms like burning sensation and regurgitation.

  • Generic Name: Domperidone + Omeprazole
  • Manufacturer: Pharma Plus
  • Medicine Form: Allopathy
  • Pregnancy Category: C

🇮🇳 acvom 10mg/20mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

acvom 10mg/20mg tablet का उपयोग मुख्य रूप से gastro intestinal और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Domperidone (10mg) + Omeprazole (20mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Domperidone + Omeprazole
Brand NameAciloc RD 20 Tablet
ManufacturerPharma Plus
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassProkinetic agent + Proton pump inhibitor
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDomperidone: Rapidly absorbed after oral administration; Omeprazole: Rapidly absorbed, delayed by food.
DistributionDomperidone: Widely distributed, crosses blood-brain barrier minimally; Omeprazole: High plasma protein binding, distributed to gastric parietal cells.
Protein BindingDomperidone: 91-93%; Omeprazole: 95%
MetabolismDomperidone: Hepatic via CYP3A4; Omeprazole: Hepatic via CYP2C19 and CYP3A4.
Half-LifeDomperidone: 7-9 hours; Omeprazole: 0.5-1 hour.
ExcretionDomperidone: Fecal (66%) and renal (32%); Omeprazole: Renal (77%) and fecal.
BioavailabilityDomperidone: 13-17%; Omeprazole: 30-40%.
Onset of ActionDomperidone: 30-60 minutes; Omeprazole: 1-2 hours.
Peak Plasma TimeDomperidone: 1-2 hours; Omeprazole: 0.5-3.5 hours.
Duration of ActionDomperidone: 4-6 hours; Omeprazole: Up to 24 hours.

Pharmacodynamics

Mechanism of ActionDomperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.
Target ReceptorDomperidone: Dopamine D2 receptors; Omeprazole: H+/K+ ATPase (proton pump).
Pharmacodynamic EffectsIncreased gastric emptying and lower esophageal sphincter pressure; Reduced gastric acid secretion.

📅 When to take acvom 10mg/20mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take acvom 10mg/20mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How acvom 10mg/20mg tablet Works

Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility; Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in parietal cells.

1 Domperidone blocks dopamine D2 receptors in the chemoreceptor trigger zone and gastrointestinal tract, increasing peristalsis and gastric emptying.
⬇️
2 Omeprazole accumulates in the acidic environment of gastric parietal cells and is converted to its active form, which irreversibly inhibits H+/K+ ATPase, reducing gastric acid secretion.

💊 acvom 10mg/20mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Gastroesophageal reflux disease (GERD), dyspepsia, gastroparesis, peptic ulcer disease.

Off-label uses: Nausea and vomiting of various etiologies, migraine-associated gastroparesis.

⚠️ What are the side effects of acvom 10mg/20mg tablet?

✅ Common Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Flatulence
  • Dry mouth

🚨 Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Extrapyramidal symptoms
  • Gynecomastia
  • Hyperprolactinemia
  • Interstitial nephritis

⚠️ Rare Side Effects

  • Hepatotoxicity
  • Anaphylaxis
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Clopidogrel Moderate Reduced antiplatelet effect
Digoxin Moderate Increased digoxin levels
Methotrexate Major Increased methotrexate toxicity

🚨 Major Interactions

  • Ketoconazole
  • Itraconazole
  • Voriconazole
  • Clarithromycin
  • Erythromycin
  • Ritonavir
  • Saquinavir
  • Telithromycin
  • Nefazodone
  • Cobicistat

⚡ Moderate Interactions

  • Warfarin
  • Cilostazol
  • Methotrexate
  • Tacrolimus
  • Fluconazole
  • Cimetidine
  • Digoxin
  • Iron salts
  • Mycophenolate mofetil

ℹ️ Minor Interactions

  • Sucralfate
  • Antacids
  • Theophylline
  • Caffeine

🍽️ Food Interactions

Omeprazole absorption may be delayed by food; Domperidone should be taken before meals.

🍷 Alcohol Interaction

Alcohol may worsen gastrointestinal irritation and reduce drug efficacy.

🛡️ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

🚫 Contraindications

Hypersensitivity to components, gastrointestinal hemorrhage, mechanical obstruction or perforation, prolactinoma, concurrent use with QT-prolonging drugs.

📊 Monitoring Parameters

ECG for QT interval, renal function, liver function, serum electrolytes, signs of extrapyramidal symptoms.

🤱 Lactation Safety

Domperidone is excreted in breast milk; omeprazole is likely excreted. Use with caution.

💊 Overdose Management

Supportive care; ECG monitoring for QT prolongation; activated charcoal if recent ingestion.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next scheduled dose.

🛑 Myths vs. Facts about acvom 10mg/20mg tablet

  • Myth: Generic substitutes of acvom 10mg/20mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Domperidone (10mg) + Omeprazole (20mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acvom 10mg/20mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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Read real stories and discussions from our patient community regarding similar health conditions.

Migraine Relief: Triggers, Treatment & Home Remedies

Namaste, and welcome to the Astitva Health Community. As your doctor, I understand how debilitating a migraine or a severe headache can be. It’s not just a “headache”—it’s a neurological storm that can stop your life in its tracks. Whether it’s the throbbing pain on one side of your head, sensitivity to light, or that nauseating feeling, you deserve relief. Let’s dive deep into understanding your triggers and the medical management that can help you regain control. Understanding Your Triggers: The Root Cause Migraines are often triggered by specific factors. Identifying these is your first step toward prevention. Common triggers in the Indian context include: Dietary Triggers: Skipping meals, eating too much masala (spices), or consuming aged cheese, processed meats, or fermented foods. Even chai or coffee withdrawal can be a trigger. Hormonal Changes: Many women experience migraines around their menstrual cycle due to fluctuating estrogen levels. Environmental Factors: Bright sunlight, strong smells (like agarbatti or perfumes), pollution, or sudden weather changes. Stress & Sleep: High stress from work, family, or exams, along with irregular sleep patterns (sleeping too little or too much), are major triggers. Dehydration & Heat: Not drinking enough water, especially during Indian summers, can easily trigger a headache. Medical Management: What Actually Works? When a migraine strikes, don’t just “bear the pain.” Here’s a step-by-step medical approach: Immediate Relief (Acute Treatment) Over-the-Counter (OTC) Medications: Paracetamol (Crocin) or Ibuprofen (Brufen) can help for mild attacks. But for severe migraines, these may not be enough. Prescription Medications: Your doctor may prescribe Triptans (like Sumatriptan or Rizatriptan) which are gold-standard for migraines. They work by constricting blood vessels in the brain. Anti-nausea drugs: If vomiting is a problem, Domperidone or Metoclopramide can help. Rest in a Dark, Quiet Room: This is not a luxury—it’s essential. Close the curtains, avoid screens, and apply a cold compress to your forehead or neck. Preventive (Prophylactic) Treatment If you have 4 or more migraine attacks per month, your doctor may recommend daily preventive medications. These include: Beta-blockers like Propranolol (often used for high BP but excellent for migraines). Antidepressants like Amitriptyline (in low doses). Antiepileptics like Topiramate or Valproate. Botox injections for chronic migraines (approved by experts). Home Remedies & Diet: Your Daily Shield Alongside medical treatment, these simple Indian remedies can make a huge difference: Stay Hydrated: Drink at least 8-10 glasses of water daily. Add a pinch of sendha namak (rock salt) and lemon for electrolytes. Ginger Tea: Boil fresh ginger in water. Ginger has anti-inflammatory properties and can reduce nausea. Adrak ki chai is a powerful ally. Magnesium-Rich Foods: Eat pumpkin seeds, almonds, spinach, and bananas. Magnesium deficiency is linked to migraines. Cold Compress: Wrap ice in a cloth and place it on your forehead or temples for 15 minutes. It numbs the pain and reduces blood flow. Peppermint Oil: Apply a drop of peppermint oil diluted with coconut oil on your temples. It has a cooling, pain-relieving effect. Avoid Processed Foods: Cut down on maida (refined flour), packaged chips, and sugary drinks. These can trigger inflammation. When to See a Doctor Immediately While most headaches are benign, you must seek urgent medical help if you experience: A sudden, explosive headache (like a “thunderclap”). Headache with fever, stiff neck, or rash. Headache after a head injury. Weakness on one side of the body, slurred speech, or vision loss. New headaches after age 50. Remember, you are not alone. Migraine is a medical condition, not a character flaw. With the right triggers management and medical plan, you can live a full, pain-free life. Stay strong, stay informed, and always consult your doctor before starting any new treatment. Take care of your astitva—your existence—because your health is your greatest wealth.

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