acutret 5 capsule allopathy (Isotretinoin (5mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acutret 5 capsule allopathy (Isotretinoin (5mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Ipca Laboratories Ltd. Contains Isotretinoin (5mg).

acutret 5 capsule - Uses, Price, Side Effects & Substitutes

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Isotretinoin (5mg) (Click to see all medicines with same salt)
🏭 Ipca Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acutret 5 capsule used for?

Acutret 10 Capsule (Isotretinoin) is used to treat Severe recalcitrant nodular acne. It contains Isotretinoin (5mg), which Reduces sebum production, normalizes follicular keratinization, inhibits Propion. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Isotretinoin
  • Manufacturer: Ipca Laboratories Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acutret 5 capsule के बारे में संक्षिप्त जानकारी (Hindi Summary)

acutret 5 capsule का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Isotretinoin (5mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Isotretinoin
Brand NameAcutret 10 Capsule
ManufacturerIpca Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassRetinoids- First generation
Route of AdministrationOral.
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed orally with high bioavailability; absorption enhanced with food.
DistributionExtensively distributed; crosses placenta; enters breast milk.
Protein Binding99.9% bound to albumin.
MetabolismHepatic metabolism via CYP450 enzymes to active metabolites (4-oxo-isotretinoin).
Half-Life20-24 hours for parent drug; longer for metabolites.
ExcretionExcreted in urine and feces equally.
Bioavailability25% (increased with food).
Onset of Action1-2 weeks for initial improvement.
Peak Plasma Time3-4 hours.
Duration of ActionTherapeutic effect persists weeks after discontinuation.

Pharmacodynamics

Mechanism of ActionReduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.
Target ReceptorRetinoic acid receptors (RARs) and retinoid X receptors (RXRs).
Pharmacodynamic EffectsDecreased sebum excretion, reduced comedogenesis, anti-inflammatory, and antimicrobial.

💡 How and when to take acutret 5 capsule?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from light and moisture.

⚙️ How acutret 5 capsule Works

Reduces sebum production, normalizes follicular keratinization, inhibits Propionibacterium acnes growth, and has anti-inflammatory effects.

1 Binds to retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in the nucleus.
⬇️
2 Modulates gene transcription involved in cell growth, differentiation, and apoptosis.
⬇️
3 Reduces sebocyte proliferation and sebum production.
⬇️
4 Normalizes follicular keratinization, preventing comedone formation.
⬇️
5 Inhibits Propionibacterium acnes growth indirectly by altering sebum composition.
⬇️
6 Exerts anti-inflammatory effects by inhibiting neutrophil chemotaxis and cytokine production.

💊 acutret 5 capsule Uses in Hindi (Ke Fayde), Benefits & Indications

Severe recalcitrant nodular acne, acne vulgaris unresponsive to other therapies.

Off-label uses: Rosacea, hidradenitis suppurativa, psoriasis, skin cancer prevention.

⚠️ What are the side effects of acutret 5 capsule?

✅ Common Side Effects

  • Cheilitis
  • Dry skin
  • Xerophthalmia
  • Epistaxis
  • Arthralgia
  • Myalgia
  • Headache
  • Increased triglycerides

🚨 Serious Side Effects

  • Pseudotumor cerebri
  • Hepatotoxicity
  • Pancreatitis
  • Depression/suicidal ideation
  • Inflammatory bowel disease
  • Teratogenicity

⚠️ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Vasculitis
  • Hearing impairment
  • Osteoporosis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for acutret 5 capsule

View All

Alternative brands with exact same active ingredient and strength (Isotretinoin (5mg)):

  1. nutret 5mg capsule
    Nuper therapeutics₹55.00💰 54.8% CHEAPER
  2. isotino 5mg capsule
    Kivi Labs Ltd₹71.50💰 41.2% CHEAPER
  3. actame 5mg tablet
    Sol Derma Pharmaceuiticals Pvt Ltd₹75.00💰 38.3% CHEAPER
  4. isotane 5mg capsule
    Micro Labs Ltd₹75.00💰 38.3% CHEAPER
  5. Tretiroz 5mg Soft Gelatin Capsule
    Dazroz Pharmaceuticals Pvt Ltd₹79.00💰 35.1% CHEAPER
  6. isopil 5 tablet
    Glowderma Labs Pvt Ltd₹80.00💰 34.2% CHEAPER
  7. isokon 5mg capsule
    Eskon Pharma₹80.00💰 34.2% CHEAPER
  8. sotret 5 mg capsule
    Sun Pharmaceutical Industries Ltd₹82.00💰 32.6% CHEAPER
  9. acwis 5mg tablet
    Blaze Remedies₹84.38💰 30.6% CHEAPER
  10. teen-tret 5 softgel capsule
    Cutis Biotech₹85.00💰 30.1% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Tetracyclines Major Increased risk of pseudotumor cerebri
Vitamin A supplements Major Additive toxicity (hypervitaminosis A)
Methotrexate Major Increased hepatotoxicity risk
Oral contraceptives Major Reduced contraceptive efficacy
Phenytoin Moderate Increased phenytoin levels
Corticosteroids Moderate Increased osteoporosis risk
Azole antifungals Moderate Increased retinoid toxicity
Alcohol Minor Increased hepatotoxicity risk
Antacids Minor Reduced isotretinoin absorption

🚨 Major Interactions

  • Tetracyclines
  • Vitamin A supplements
  • Methotrexate
  • Oral contraceptives (reduced efficacy)

⚡ Moderate Interactions

  • Phenytoin
  • Corticosteroids
  • Antifungals (azole)

ℹ️ Minor Interactions

  • Alcohol
  • Antacids

🍽️ Food Interactions

High-fat meals increase absorption.

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, breastfeeding, hypersensitivity to retinoids, hypervitaminosis A, severe hepatic impairment.

📊 Monitoring Parameters

Liver function tests, serum lipids, pregnancy test (monthly), CBC, renal function.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Supportive care; symptoms include headache, vomiting, facial flushing, cheilitis, abdominal pain. No specific antidote.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🛑 Myths vs. Facts about acutret 5 capsule

  • Myth: Generic substitutes of acutret 5 capsule are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Isotretinoin (5mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acutret 5 capsule can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Bhai, onion juice se baal aayenge ya sirf ghar ka atmosphere bigdega? 🧅💨

Bc ye onion juice trend dekh ke lagta hai sab log pagal ho gaye hain. Mera dost roz subah pyaz ka juice nikal ke daagta hai head pe, aur ghar mein aisi smell aati hai jaise kitchen mein koi ro raha ho 😂. Uska kehna hai 2 hafte mein results dikhne lage, but honestly I think woh bas apne aap ko convince kar raha hai. Main khud minoxidil try kar raha hoon lekin side effects se darr lagta hai. Onion juice toh natural hai, but kya sach mein kaam karta hai ya bas placebo? Kisi ne try kiya hai? Mera hairline pehle hi retreat ho rahi hai aur friends "takle" bol ke chidhate hain. Ek baar to class mein sab ke saamne "bald spot" ka joke maar diya, gussa aaya but kya kar sakta hoon. Dermatologist ke paas gaya tha toh usne minoxidil suggest kiya, lekin online log bol rahe hai onion juice bhi effective hai. Par honestly, pyaz ki smell 24x7 tolerate karna possible hai? Aur agar koi side effect hua toh? Pls share your experience if you have tried this. Koi genuine advice chahiye, bas bakwas nahi.

Relative ne face dekha toh ghar ke nuskhe pe lecture de diya 😭 Cystic acne scars ka koi asli solution do yaar!

Yaar itni frustration ho rahi hai 😭. Kal mera ek relative aaya and straight up bola, “Beta face pe ye kya ho gaya? Chandan lagao, besan lagao.” Jaise maine kuch try nahi kiya! I know they mean well but itna irritating hota hai jab woh samajhte hain ki ghar ke nuskhe se sab theek ho jayega. Cystic acne hai bhai, ye normal pimple nahi hai. Aur maine jo pimple popping ki aadat daali hai na, uske daag ab permanently hi dikhte hain lagta hai. Koi genuine tips do please. I’m currently using niacinamide serum and aloe vera gel, but scars ka koi fark nahi pad raha. Koi specific cream ya dermatologist ka koi remedy batado jo kaam kare? Sunscreen bhi lagati hoon lekin glow nahi aa raha. Filter ke bina selfie lene ka mann nahi karta ab. 😔 Aur haan, please “haldi aur doodh” mat bolna, woh try kar chuki hoon. Kuch actual skincare routine chahiye jo cystic acne scars ke liye effective ho. Pls help! 🙏

2 mahine se baal jhad rahe, kya koi solution hai? 🥲

Ya Allah yaar, please koi batao. Mera to pichle 2 mahine se itna hair fall ho raha hai ki nahaate waqt haath me guchche aa rahe hain. Aaj subah comb karte waqt to rona aa gaya, comb me itne saare baal ki lagta hai chemo kar rahi hoon main. 😭 Maine socha tha pregnancy ke baad thoda normal hai lekin ye to extreme ho gaya hai. Baby bhi raat bhar sota nahi, 3-4 baar uthti hoon, neend poori nahi hoti aur upar se ye hair fall. Saas bolti hain "patli doodh piya karo, mali ka tel lagao" lekin kuch kaam nahi kar raha. Maine coconut oil bhi lagaya, onion juice bhi try kiya lekin koi farak nahi. Kya koi hai jiska same experience hua? Yeh kab rukta hai? Koi shampoo ya treatment recommend karo jo actually kaam kare. Dermatologist ke paas jaana hai but baby ke saath bahar jaana mushkil hai. Please help yaar, aaj kal mirror me dekhna bhi pasand nahi kar rahi. 🙏

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