Acticlox Capsule (Amoxycillin + Cloxacillin) - Uses, Price, Side Effects
What is acticlox capsule used for?
Acticlox Capsule is a combination antibiotic containing Amoxycillin and Cloxacillin. It is used to treat bacterial infections such as respiratory tract infections, skin infections, and soft tissue infections. Amoxycillin works by inhibiting bacterial cell wall synthesis, while Cloxacillin is effective against penicillinase-producing bacteria, providing broad-spectrum coverage.
- Generic Name: Amoxycillin + Cloxacillin
- Manufacturer: Synthiko Formulations & Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acticlox capsule Uses & Benefits
Infections caused by susceptible organisms including respiratory tract infections, skin and soft tissue infections, urinary tract infections, osteomyelitis, septicemia.
Off-label uses: Prophylaxis in dental procedures (not standard); some uses in Lyme disease.
๐ Drug Information
| Generic Name(s) | Amoxycillin + Cloxacillin |
| Brand Name | Amyclox-LB Capsule |
| Manufacturer | Synthiko Formulations & Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Penicillin antibiotics, beta-lactamase resistant combination |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Amoxycillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); Cloxacillin inhibits cell wall synthesis and is resistant to staphylococcal beta-lactamase.
Mechanism Steps
๐ก How to Take acticlox capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of acticlox capsule
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Skin rash
- Urticaria
๐จ Serious Side Effects
- Anaphylaxis
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- Seizures (high doses)
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Interstitial nephritis
- Hepatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Probenecid | Moderate | Decreased renal excretion of amoxicillin |
| Oral contraceptives | Minor | Reduced contraceptive efficacy |
๐จ Major Interactions
- Methotrexate
- Warfarin
- Probenecid
โก Moderate Interactions
- Oral contraceptives
- Allopurinol
- Chloramphenicol
โน๏ธ Minor Interactions
- Tetracyclines
- Sulfonamides
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
Avoid alcohol; may increase risk of hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to penicillins or cephalosporins; history of penicillin-associated anaphylaxis.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of hypersensitivity.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.
๐ Overdose Management
Gastric lavage, activated charcoal; supportive measures; hemodialysis may help.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose.