aclonec plus 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aclonec plus 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Allenchem. Contains Aceclofenac (100mg) + Paracetamol (325mg).

Aclonec Plus 100mg/325mg Tablet - Uses, Price, Side Effects

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🏭 Allenchem 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aclonec plus 100mg/325mg tablet used for?

Aclonec Plus 100mg/325mg Tablet is a combination medicine containing Aceclofenac (100mg) and Paracetamol (325mg). It is used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and dental pain. Aceclofenac works by blocking COX enzymes, reducing prostaglandins, while Paracetamol acts on the central nervous system to lower fever and pain. Take as directed by your doctor.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Allenchem
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aclonec plus 100mg/325mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aclonec plus 100mg/325mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerAllenchem
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

📅 When to take aclonec plus 100mg/325mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take aclonec plus 100mg/325mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How aclonec plus 100mg/325mg tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 aclonec plus 100mg/325mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of aclonec plus 100mg/325mg tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about aclonec plus 100mg/325mg tablet

  • Myth: Generic substitutes of aclonec plus 100mg/325mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aclonec plus 100mg/325mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

15 din se भूख ही नहीं! UPSC stress ने मेरा appetite मार दिया 😭 कोई remedy बताओ?

Yaar kya karu, pichle 15 din se khane ka Mann nahi karta. Subah utho to pet nahi lagta, coaching jaane se pehle bas ek biscuit kha lo. Lunch time bhi skip ho jata hai, raat ko ghar aake kuch khane ka man karta hai but tab tak itna thak jaati hu ki so jati hu. Aaj morning mummy ne phone karke pucha ki kya khaya, to maine jhooth bol diya ki sab kuch theek hai. Par sach ye hai ki pichle hafte 2 kg weight kam ho gaya hai. Dosto ne notice kiya, bol rahe the ki tum bahut patli ho gayi ho. But main kya karu, UPSC ka pressure itna hai ki khana bhi bhool jaati hu. Kal hi ek batchmate ne kaha ki stress se hair fall bhi ho raha hai aur appetite bhi mar raha hai. Kisi ne try kiya hai kuch remedy? Main ne socha ki chhote meals try kare, jaise fruit ya juice, but kuch acha lagta nahi. Bas raat ko dudh peeti hu, but woh bhi force karke. Batao yaar, kya kare? Koi natural appetite booster ho toh batado. Bahut desperate hu.

Raat ko body aag jaise jalna? Koi remedy batao ya doctor dikhaun? 😩

Yaar, raat ko neend se achanak jaag jaana aur poora body aag jaise jalna - koi hai jo samajh sakta hai mujhe? 😩 Pichle kuch hafte se aisa ho raha hai. Kal raat to itna garmi lagi ki AC 18° pe bhi chain nahi mila. Pati kehti hain, "Kya hua? Fever hai kya?" Main bolti hoon, "Kuch nahi, bas menopause ka mamla." Unko toh pata bhi nahi hota ye kya hota hai. Ek doston ne kaha tha, "Fenugreek seeds bhigokar piyo, thoda aaram milega." Maine try kiya, lekin kuch khaas fark nahi aaya. Kya koi aur remedy hai jo kaam karta hai? Ya koi specific doctor se milna chahiye? Please suggest karo, main raat ko deewar se sar takne laga hoon. Bas neend chahiye. 🙏

High BP? 10 Indian Foods to Lower It Fast

High blood pressure, or High BP (Hypertension), is a silent but serious health concern affecting millions of Indians today. The good news? You don't always need medicine to bring it down quickly. Your kitchen is your first line of defence. As an Indian doctor, I have seen patients lower their BP naturally by making simple, traditional dietary changes. Let me share the Top 10 Indian foods that can help you manage hypertension effectively and quickly. Why is High BP rising in India? Before we dive into the foods, understand the common triggers: excess salt (namak), stress, lack of sleep, and a diet rich in processed foods. Many of us eat pickle, papad, and chutney daily—these are hidden salt bombs. The DASH diet (Dietary Approaches to Stop Hypertension) is globally recommended, but an Indian version is even more effective because it uses our local spices and ingredients. Top 10 Indian Foods to Lower BP Quickly 1. Banana (Kela) Bananas are rich in potassium, which helps flush out excess sodium from your body. Eat one medium banana daily—it’s a quick, portable snack that balances your electrolytes. 2. Curd (Dahi) & Buttermilk (Chaas) Probiotic-rich curd and buttermilk are excellent for BP. Chaas with roasted cumin (jeera) and black salt (kala namak in moderation) is a cooling drink. Avoid adding too much salt. It helps reduce inflammation and improves gut health, which is linked to BP control. 3. Leafy Greens (Palak, Methi, Bathua) Spinach (palak), fenugreek (methi), and bathua are loaded with magnesium, potassium, and nitrates. These nutrients relax blood vessels. Make a simple sabzi or add them to dal. Avoid overcooking to retain nutrients. 4. Oats (Jai) & Ragi (Nachni) Oats and ragi are high in soluble fiber and magnesium. They help lower cholesterol and BP. Start your day with a bowl of oats or ragi porridge. Avoid adding sugar—use a pinch of cinnamon instead. 5. Garlic (Lehsun) Garlic contains allicin, a compound that relaxes blood vessels. Chew 1-2 raw cloves on an empty stomach or add crushed garlic to your sabzi. It can lower BP within a few hours. 6. Beetroot (Chukandar) Beetroot is rich in nitrates, which convert to nitric oxide in the body, widening blood vessels. Drink a small glass of beetroot juice (without salt) daily—it can lower systolic BP by 4-5 points in just a few hours. 7. Watermelon (Tarbooz) Watermelon contains L-citrulline, an amino acid that helps produce nitric oxide. Eat a bowl of watermelon or drink its juice (no sugar). It’s also hydrating, which is crucial for BP. 8. Flaxseeds (Alsi) & Chia Seeds These tiny seeds are packed with omega-3 fatty acids and fiber. Soak 1 tablespoon of flaxseeds in water overnight and eat in the morning. They help reduce inflammation and improve artery function. 9. Turmeric (Haldi) Turmeric’s active compound curcumin is a powerful anti-inflammatory. Drink a glass of warm milk with a pinch of turmeric (haldi doodh) before bed. It helps lower BP by reducing oxidative stress. 10. Coconut Water (Nariyal Pani) Fresh coconut water is naturally rich in potassium and magnesium. Drink one glass of tender coconut water daily—it’s a natural diuretic that helps flush out excess sodium. Quick Action Plan: What to Do Right Now Reduce salt: Avoid adding extra salt to your food. Use herbs, lemon juice, or amchur (dry mango powder) instead. Walk for 15 minutes: After eating any of these foods, a short walk helps the nutrients work faster. Stay hydrated: Drink 8-10 glasses of water daily. Dehydration can spike BP. When to See a Doctor These foods are powerful, but they are not a substitute for medical treatment. If your BP is consistently above 140/90 mmHg, or if you experience severe headache, chest pain, shortness of breath, or vision changes, seek immediate medical help. Always consult your doctor before making major dietary changes, especially if you are on medication. Your health is in your hands—start with one food today and feel the difference.

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