acito p 100mg/500mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acito p 100mg/500mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Santo Formulations. Contains Aceclofenac (100mg) + Paracetamol (500mg).

Acito P 100mg/500mg Tablet - Uses, Price, Side Effects

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🏭 Santo Formulations 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acito p 100mg/500mg tablet used for?

Acito P 100mg/500mg Tablet is a combination of Aceclofenac and Paracetamol used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and dental pain. Aceclofenac works by blocking prostaglandin synthesis, while Paracetamol reduces fever and pain. Take it as directed by your doctor.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Santo Formulations
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acito p 100mg/500mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

acito p 100mg/500mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerSanto Formulations
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

📅 When to take acito p 100mg/500mg tablet?

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

💡 How and when to take acito p 100mg/500mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How acito p 100mg/500mg tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 acito p 100mg/500mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of acito p 100mg/500mg tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Aspirin Moderate Increased risk of gastrointestinal bleeding
Lithium Moderate Increased lithium levels
ACE inhibitors Minor Reduced antihypertensive effect

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about acito p 100mg/500mg tablet

  • Myth: Generic substitutes of acito p 100mg/500mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (500mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acito p 100mg/500mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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PCOS (Polycystic Ovary Syndrome) ek aam hormonal condition hai jo aaj kal ki zindagi mein bohot si Indian women ko affect karti hai. Iske do common symptoms hain: bal ka jhadna (hair fall) aur weight gain. Yeh dono problems ek doosre se judi hui hain, kyunki insulin resistance aur hormonal imbalance dono ko trigger karti hain. Lekin ghabrane ki zaroorat nahi hai. Sahi ghar ke nuskhe aur lifestyle changes se aap in problems ko control kar sakti hain. PCOS mein hair fall aur weight gain kyun hota hai? PCOS mein ovaries extra androgens (male hormones jaise testosterone) produce karti hain. Isse insulin resistance hota hai, jisse body sugar ko properly use nahi kar pati. Insulin resistance weight gain ko trigger karta hai, khaaskar pet ke area mein. Saath hi, high androgen levels hair follicles ko weaken karte hain, jisse scalp se baal jhadne lagte hain (androgenetic alopecia). Best home remedies for PCOS hair fall Amla (Indian gooseberry) juice: Amla vitamin C aur antioxidants se bharpoor hota hai. Roz subah khali pet 1 tablespoon amla juice piyen. Isse scalp health improve hoti hai aur hair fall control hota hai. Fenugreek (methi) seeds: 2 tablespoons methi dana raat bhar bhigokar subah iska paste bana lein. Isse scalp par 20 minutes lagayein, phir shampoo karein. Methi biotin aur protein se hair follicles ko nourish karta hai. Coconut oil + Curry leaves: Coconut oil mein curry leaves garam karke massage karein. Curry leaves hair growth boost karte hain aur oil scalp ko moisturize karta hai. Green tea rinse: Green tea mein antioxidants hote hain jo DHT (hormone jo hair fall karta hai) ko block karte hain. Thande green tea se hair rinse karein. Best home remedies for PCOS weight gain Lemon water with honey: Subah khali pet gungune paani mein 1 lemon juice aur 1 teaspoon honey mix karein. Yeh metabolism boost karta hai aur insulin sensitivity improve karta hai. Cinnamon (dalchini) tea: 1 teaspoon cinnamon powder ko 1 cup garam paani mein 10 minutes bhigokar piyen. Cinnamon blood sugar ko regulate karta hai, jo weight loss mein madad karta hai. Jeera (cumin) water: 1 teaspoon jeera ko 1 cup paani mein raat bhar bhigokar subah piyen. Jeera digestion improve karta hai aur bloating reduce karta hai. Apple cider vinegar (ACV): 1 tablespoon ACV ko 1 glass water mein mix karke khane se pehle piyen. ACV insulin sensitivity improve karta hai aur weight loss support karta hai. Lifestyle changes jo PCOS mein zaroori hain Low-GI diet follow karein: White rice, roti aur sugar ki jagah brown rice, whole wheat roti, oats, quinoa aur sabziyon ko prefer karein. Isse blood sugar stable rahta hai. Protein aur fiber zyada khaayein: Eggs, chicken, fish, paneer, legumes, aur leafy greens. Protein aur fiber hunger cravings reduce karte hain aur weight loss fast karte hain. Exercise regularly: Roz 30-45 minutes walking, yoga, ya strength training karein. Yoga poses jaise Surya Namaskar aur Kapalbhati PCOS symptoms improve karte hain. Stress kam karein: Stress hormones (cortisol) PCOS ko worsen karte hain. Meditation, deep breathing, ya hobbies ke liye time nikalein. Sleep cycle fix karein: Roz 7-8 hours ki neend lein. Late night jaagna hormonal balance disturb karta hai. When to see a doctor? Agar aapke hair fall severe ho raha hai (jaise ek baar mein baal ke guchhe jhadna) ya weight gain uncontrolled hai (1-2 mahine mein 5-6 kg), toh turant doctor se milein. Agar home remedies ke baad bhi 3-4 mahine mein koi improvement nahi dikhti, toh endocrinologist ya gynecologist se consult karein. PCOS manageable hai, lekin professional guidance kabhi kabhi zaroori hoti hai. Yaad rakhein, PCOS ek journey hai, race nahi. Chhoti chhoti lifestyle changes aur ghar ke nuskhe aapko ismein bahut madad karenge. Astitva Health Community aapke saath hai, har kadam par.

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