acithio-plus tablet allopathy (Aceclofenac (100mg) + Thiocolchicoside (4mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acithio-plus tablet allopathy (Aceclofenac (100mg) + Thiocolchicoside (4mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Accilex Nutricorp. Contains Aceclofenac (100mg) + Thiocolchicoside (4mg).

acithio-plus tablet - Uses, Price, Side Effects & Substitutes

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🏭 Accilex Nutricorp 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acithio-plus tablet used for?

Aldigesic TH 100mg/4mg Tablet (Aceclofenac + Thiocolchicoside) is used to treat Acute musculoskeletal pain. It contains Aceclofenac (100mg) + Thiocolchicoside (4mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolc. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Thiocolchicoside
  • Manufacturer: Accilex Nutricorp
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acithio-plus tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

acithio-plus tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Thiocolchicoside (4mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

📋 Drug Information

Generic Name(s)Aceclofenac + Thiocolchicoside
Brand NameAldigesic TH 100mg/4mg Tablet
ManufacturerAccilex Nutricorp
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Muscle Relaxant
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture and light
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99% bound to plasma proteins; Thiocolchicoside: ~13% bound
MetabolismAceclofenac: Hepatic via CYP2C9 to diclofenac; Thiocolchicoside: Hepatic glucuronidation
Half-LifeAceclofenac: ~4 hours; Thiocolchicoside: ~7 hours
ExcretionAceclofenac: Renal (70-80% as metabolites); Thiocolchicoside: Renal (70% as glucuronide) and fecal
BioavailabilityAceclofenac: ~100%; Thiocolchicoside: ~25%
Onset of ActionAceclofenac: 30-60 minutes; Thiocolchicoside: 1-2 hours
Peak Plasma TimeAceclofenac: 1-3 hours; Thiocolchicoside: 1-2 hours
Duration of ActionAceclofenac: 12 hours; Thiocolchicoside: 24 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation
Target ReceptorCOX-1, COX-2 (Aceclofenac); GABA-A receptor, glycine receptor (Thiocolchicoside)
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic, muscle relaxant

💡 How and when to take acithio-plus tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture and light

⚙️ How acithio-plus tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation

1 Aceclofenac inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis from arachidonic acid.
⬇️
2 Decreased prostaglandins lead to reduced inflammation, pain, and fever.
⬇️
3 Thiocolchicoside binds to GABA-A receptors and glycine receptors in the spinal cord and brainstem.
⬇️
4 This enhances inhibitory neurotransmission, leading to muscle relaxation.
⬇️
5 Combined effect: analgesia and relief of muscle spasm.

💊 acithio-plus tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle spasms

Off-label uses: Postoperative pain, dental pain, dysmenorrhea

⚠️ What are the side effects of acithio-plus tablet?

✅ Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Dizziness
  • Headache
  • Somnolence
  • Abdominal pain
  • Dyspepsia

🚨 Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Hepatotoxicity
  • Nephrotoxicity
  • Cardiovascular events
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Bone marrow suppression

⚠️ Rare Side Effects

  • Pancreatitis
  • Hearing loss
  • Tinnitus
  • Aseptic meningitis
  • Photosensitivity
  • Agranulocytosis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for acithio-plus tablet

View All

Alternative medicines with exact same composition and strength (Aceclofenac (100mg) + Thiocolchicoside (4mg)):

  1. davaindia aceclofenac+thiocolchicoside 100mg/4mg tablet
    Davaindia Generic Pharmacy₹60.00💰 58.7% CHEAPER
  2. dinal-mx tablet
    Sapco Laboratories Pvt Ltd₹61.88💰 57.4% CHEAPER
  3. xynac th 100mg/4mg tablet
    Arlak Biotech Pvt Ltd₹65.00💰 55.3% CHEAPER
  4. alecta th 100mg/4mg tablet
    SandMartin Pharmaceuticals Pvt Ltd₹73.13💰 49.7% CHEAPER
  5. azithoril ap 4mg/100mg/325mg tablet
    Azilliane Healthcare₹74.06💰 49% CHEAPER
  6. inflamex tablet
    Excella Life Sciences Pvt Ltd₹77.00💰 47% CHEAPER
  7. synid th 100mg/4mg tablet
    Astonea Labs Private Limited₹78.00💰 46.3% CHEAPER
  8. Thicop AP 4mg/100mg/325mg Tablet
    Pasco Pharmaceuticals₹78.00💰 46.3% CHEAPER
  9. abflam th 4mg/100mg/325mg tablet
    Absolute Medicare Solutions Pvt Ltd₹79.00💰 45.6% CHEAPER
  10. ceknac th 100mg/4mg tablet
    DR Best pharmaceuticals Pvt Ltd₹85.00💰 41.5% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulceration risk
Corticosteroids Major Increased GI bleeding risk
Diuretics Major Reduced diuretic efficacy
ACE inhibitors Major Reduced antihypertensive effect
Cyclosporine Major Increased nephrotoxicity
SSRIs Moderate Increased bleeding risk
Alcohol Moderate Increased GI bleeding and hepatotoxicity

🚨 Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Anticoagulants
  • Aspirin
  • Corticosteroids
  • Diuretics
  • ACE inhibitors
  • Cyclosporine
  • Tacrolimus

⚡ Moderate Interactions

  • SSRIs
  • SNRIs
  • Antiplatelet agents
  • Pentoxifylline
  • Zidovudine
  • Pemetrexed

ℹ️ Minor Interactions

  • Beta-blockers
  • Digoxin
  • Phenytoin
  • Sulfonylureas

🍽️ Food Interactions

May be taken with food to reduce GI upset; avoid alcohol

🍷 Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, bleeding disorders, severe renal/hepatic impairment, pregnancy, lactation, children <18 years, history of asthma, CVS disease

📊 Monitoring Parameters

Liver function, renal function, CBC, blood pressure, signs of GI bleeding

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal; monitor for GI bleeding, renal function, CNS depression

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose

🛑 Myths vs. Facts about acithio-plus tablet

  • Myth: Generic substitutes of acithio-plus tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Thiocolchicoside (4mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acithio-plus tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Winter Knee Pain? 5 Ayurvedic Gharelu Nuskhe Turant Aazmao

Winter ka mausam aate hi ghaton aur jodon mein dard (joint pain) aur akadhan (stiffness) badh jaana ek aam samasya hai, khaaskar un logon ke liye jo ghutno ke dard (knee pain) ya arthritis se pehle se pareshan hain. Astitva Health Community mein aapka swagat hai. Main aaj aapko kuch aise Ayurvedic aur ghar ke nuskhe batane wala hoon jo is mausam mein aapke ghutno ko rahat de sakte hain aur aapki zindagi ko aasan bana sakte hain. Kyun badhta hai winter mein knee pain? Thandak ke mausam mein Vata dosha (Ayurveda ke anusar hawa aur space ka tatva) badh jaata hai. Vata dosha ka sambandh jodon mein lubrication aur flexibility se hota hai. Jab yeh dosha badhta hai, toh jodon mein stiffness, cracking sound, aur dard badh jaata hai. Iske alawa, thandak mein hum kam harkat karte hain, jisse muscles weak ho jaate hain aur cartilage par pressure padta hai. Home Remedies for Knee Pain in Winter 1. Ayurvedic Tail (Oil) Massage Garm tail se massage karna sabse asardar upay hai. Mahanarayan tail ya Balashwagandha tail ko halka garam karein aur ghutno par 10-15 minute tak dheere-dheere malish karein. Isse vata dosha shant hota hai, blood circulation badhti hai, aur jodon ki stiffness kam hoti hai. Raat ko sone se pehle yeh massage karna behtar hai. 2. Turmeric and Ginger Tea Haldi (turmeric) aur adrak (ginger) mein natural anti-inflammatory properties hoti hain. Ek cup pani mein 1 choti adrak ka tukda aur 1/2 chai chamach haldi powder daal kar 5-7 minute ubaalein. Ismein thoda sa shahad (honey) aur nimbu (lemon) mila kar piyen. Rozana 2 baar seene se dard aur swelling mein kami aati hai. 3. Epsom Salt Bath Garm paani mein Epsom salt (magnesium sulfate) daal kar 15-20 minute tak ghutno ko bhigo kar rakhein. Yeh muscles ko relax karta hai, pain kam karta hai, aur joint stiffness ko door karta hai. Hafta mein 2-3 baar karein. Diet Tips for Winter Arthritis Garm aur pake hue khana: Thandak ke mausam mein kacchi sabziyan aur salad se bachein. Iske bajaye soup, khichdi, aur ghee wali roti khayen. Ghee joints ko lubricate karta hai. Omega-3 rich foods: Alsi ke beej (flaxseeds), akharot (walnuts), aur chia seeds ka sevan karein. Yeh inflammation kam karte hain. Haldi wala doodh: Raat ko sone se pehle 1 glass garm doodh mein 1/2 chai chamach haldi aur chutki bhar kali mirch (black pepper) daal kar piyen. Kali mirch haldi ke absorption ko badhati hai. Masala chai: Adrak, dalchini (cinnamon), laung (clove), aur elaichi (cardamom) wali chai piyen. Yeh vata dosha ko shant karta hai. Lifestyle Changes for Relief Halki exercise: Thandak mein bhi rozana 10-15 minute stretching ya yoga (jaise Tadasana, Vrikshasana) karein. Isse muscles strong rehte hain. Garm kapde pehne: Ghutno ko dhakne ke liye woolen knee caps ya pati (bandage) ka istemal karein. Thandak se bachna sabse zaroori hai. Pani piyen: Thandak mein pyaas kam lagti hai, lekin hydration joint lubrication ke liye zaroori hai. Rozana 8-10 glass garm pani piyen. Kab doctor se milein? Agar ghar ke nuskhe aur Ayurvedic upay karne ke baad bhi dard 2-3 hafton mein kam nahi hota, ya aapko tez swelling, redness, ya bukhar (fever) ho jaye, toh turant orthopaedic doctor se sampark karein. Yeh infection ya severe arthritis ka sanket ho sakta hai. Yaad rakhein, winter mein knee pain ko ignore karna dangerous ho sakta hai. Astitva Health Community mein hum aapki sehat ke liye yahan hain. Apne sawaal comments mein zaroor poochhiye!

68 ke umar mein pota ke saath khelna hai! Koi gharelu nuskha ya aasan exercise batao

Namaste doston. Aaj mera pota, 10 saal ka chhota hai, usne mujhe yeh site bataya aur sikhaya ki aap sab se baat kaise karein. Bahut ajeeb laga pehle, par ab thoda maza aa raha hai. Maine socha, aaj subah uth ke thoda chalne ki koshish ki, bas ghar ke bahar 200 kadam hi chal paaya, saans phool gayi. Pota bolta hai, "Dada, aap doctor se pucho, shayad kuch naya dawa ho." Lekin doctor to pehle hi bol chuke hain, zyada mehnat nahi karna. Ab lagta hai, bypass ke baad bhi dil kamzoor ho raha hai. Koi aapas mein koi gharelu nuskha bataye? Jaise adrak aur shahad ka pani peena, kya faida hoga? Ya phir koi aasan exercise ho to batao. Main 68 ka hoon, lekin ab bhi thoda active rehna chahta hoon. Pota ke saath khelna hai, usko park le jaana hai. Aap sab ka experience sunkar achha lagega. Dhanyavaad.

BP-Sugar ka khel, dil ka dard — kya aasan exercise ghar pe karein?

Namaste doston. Aaj subah thoda sa bazaar gaya tha, bas paas ki dukaan tak, lekin wapas aate aate saans phool gayi. Biwi ne kaha "itna kaam kyun kar rahe ho, aaram karo". Par main kya karun, ghar mein reh reh ke bore ho jaata hoon. Pichhle hafte doctor ne kaha tha ki BP aur sugar control mein rakho, lekin ye dil ka dard kabhi kabhi achanak aata hai. Ek chhota sa sawaal hai aap sab se - kya koi aisi aasan exercise hai jo ghar baithe kar sakte hoon? Pota kehta hai "dada ji aap yoga karo", par mujhe lagta hai ki zyada jhukna ya utna karna meri umar mein theek nahi. Kripya koi sahi raah bataye. Aur haan, subah uthke ek glass halka garam paani mein shahad aur nimbu le raha hoon, kya ye heart ke liye theek hai ya nahi? Aap sab ke anubhav ka intzaar rahega. Dhanyavaad.

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