acicul syrup - Magaldrate (480mg) + Dimethicone (20mg) medicine

Acicul Syrup - Uses, Price, Side Effects, Composition

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๐Ÿญ Arehk Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is acicul syrup used for?

Acicul Syrup is a combination medicine containing Magaldrate (480mg) and Dimethicone (20mg). It is used to treat acidity, heartburn, and gas. Magaldrate neutralizes excess stomach acid, while Dimethicone reduces gas and bloating, providing quick relief from digestive discomfort.

  • Generic Name: Magaldrate + Dimethicone
  • Manufacturer: Arehk Healthcare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š acicul syrup Uses & Benefits

Symptomatic relief of hyperacidity, heartburn, dyspepsia, and flatulence.

Off-label uses: Not commonly used off-label.

๐Ÿ“‹ Drug Information

Generic Name(s)Magaldrate + Dimethicone
Brand NameAcicul Syrup
ManufacturerArehk Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntacid + Antiflatulent
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC); protect from freezing.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption; acts locally in GI tract.
DistributionNot significantly distributed due to local action.
Protein BindingNot applicable (minimal systemic absorption).
MetabolismNot metabolized; acts locally.
Half-LifeNot applicable (local action).
ExcretionEliminated in feces.
BioavailabilityNot applicable (local action).
Onset of ActionRapid (minutes).
Peak Plasma TimeNot applicable (local action).
Duration of Action1-2 hours.

How It Works

Magaldrate neutralizes gastric acid; Dimethicone reduces surface tension of gas bubbles, facilitating their expulsion.

Mechanism Steps

1Magaldrate reacts with gastric acid to form magnesium and aluminum salts, neutralizing pH.
2Dimethicone reduces surface tension of gas bubbles, promoting coalescence and expulsion.

๐Ÿ’ก How to Take acicul syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of acicul syrup

โœ… Common Side Effects

  • Diarrhea
  • Constipation
  • Nausea
  • Vomiting

๐Ÿšจ Serious Side Effects

  • Hypermagnesemia (rare)
  • Hypophosphatemia (prolonged use)

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Metabolic alkalosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tetracyclines Moderate Reduced absorption of tetracyclines
Anticholinergics Moderate Increased anticholinergic side effects

๐Ÿšจ Major Interactions

  • Tetracyclines
  • Fluoroquinolones
  • Iron salts
  • Digoxin
  • Mycophenolate

โšก Moderate Interactions

  • Bisphosphonates
  • Sodium polystyrene sulfonate
  • Elvitegravir

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • Vitamin D analogs

๐Ÿฝ๏ธ Food Interactions

Milk and dairy products may reduce efficacy.

๐Ÿท Alcohol Interaction

No significant interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component; severe renal impairment; hypophosphatemia.

๐Ÿ“Š Monitoring Parameters

Serum magnesium and phosphate in prolonged use or renal impairment.

๐Ÿคฑ Lactation Safety

Likely safe; minimal systemic absorption.

๐Ÿ’Š Overdose Management

Gastric lavage; supportive measures; monitor electrolytes.

โฐ Missed Dose

Take as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

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