acicloder 200mg tablet - Acyclovir (200mg) medicine

acicloder 200mg tablet - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Elder Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is acicloder 200mg tablet used for?

Acivir 400 DT Tablet (Acyclovir) is used to treat ANTI INFECTIVES. It contains Acyclovir (200mg), which Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, the. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Acyclovir
  • Manufacturer: Elder Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š acicloder 200mg tablet Uses & Benefits

Herpes simplex infections (genital, oral, encephalitis), varicella-zoster (chickenpox, shingles).

Off-label uses: Herpes simplex prophylaxis in immunocompromised, EBV infection

๐Ÿ“‹ Drug Information

Generic Name(s)Acyclovir
Brand NameAcivir 400 DT Tablet
ManufacturerElder Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntiviral (Non-HIV) drugs
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAcyclovir is only partially absorbed from the gastrointestinal tract; oral bioavailability is 15-30%.
DistributionWidely distributed; crosses the blood-brain barrier and placenta; appears in breast milk.
Protein Binding9-33%
MetabolismHepatic; minor metabolism by aldehyde oxidase and alcohol dehydrogenase.
Half-Life2.5-3.3 hours (normal renal function); up to 20 hours in end-stage renal disease.
ExcretionRenal (62-90% as unchanged drug) via glomerular filtration and tubular secretion.
Bioavailability15-30%
Onset of ActionNot well defined; antiviral effect begins after conversion to active triphosphate.
Peak Plasma Time1.5-2 hours
Duration of ActionApproximately 8 hours (dosing interval dependent on renal function).

How It Works

Acyclovir is converted to acyclovir monophosphate by viral thymidine kinase, then to triphosphate by cellular kinases, which inhibits viral DNA polymerase and incorporates into viral DNA, causing chain termination.

Mechanism Steps

1Acyclovir enters virus-infected cells.
2Viral thymidine kinase converts acyclovir to acyclovir monophosphate.
3Cellular kinases convert monophosphate to diphosphate and triphosphate.

๐Ÿ’ก How to Take acicloder 200mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of acicloder 200mg tablet

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Fatigue

๐Ÿšจ Serious Side Effects

  • Acute renal failure
  • Neurotoxicity (confusion, hallucinations, seizures)
  • Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS)

โš ๏ธ Rare Side Effects

  • Hepatitis
  • Stevens-Johnson syndrome
  • Anaphylaxis
  • Leukopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Probenecid Major Reduced renal clearance of acyclovir, increased plasma levels and toxicity risk.
Cimetidine Major Increased acyclovir AUC and half-life.
Mycophenolate mofetil Major Increased plasma levels of both drugs; monitor for toxicity.
Tenofovir Moderate Additive nephrotoxicity risk.
Aminoglycosides Moderate Increased risk of nephrotoxicity.
Cyclosporine Moderate Increased nephrotoxicity risk.
Tacrolimus Moderate Increased nephrotoxicity risk.
Zidovudine Minor Possible increased drowsiness.
Interferon Minor Possible additive antiviral effect.

๐Ÿšจ Major Interactions

  • Probenecid
  • Cimetidine
  • Mycophenolate mofetil

โšก Moderate Interactions

  • Tenofovir
  • Aminoglycosides
  • Cyclosporine
  • Tacrolimus

โ„น๏ธ Minor Interactions

  • Zidovudine
  • Interferon

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

No known interaction; however, alcohol may exacerbate side effects like dizziness.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to acyclovir or valacyclovir.

๐Ÿ“Š Monitoring Parameters

Renal function (especially in elderly or high-dose therapy); hydration status.

๐Ÿคฑ Lactation Safety

Caution; acyclovir is excreted in breast milk but considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for acicloder 200mg tablet

View All

Alternative brands with exact same active ingredient (Acyclovir (200mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install