ache x tablet - Uses, Price, Side Effects & Substitutes
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Medically Reviewed
By SaathiMed Expert Medical Panel
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💊 What is ache x tablet used for?
Ache X Tablet (Chlorzoxazone + Diclofenac) is used to treat Acute musculoskeletal pain. It contains Chlorzoxazone (250mg) + Diclofenac (50mg), which Chlorzoxazone: Depresses CNS; Diclofenac: Inhibits COX-1/2. Always consult your doctor before use. Take as prescribed.
💊 Generic Name
Chlorzoxazone + Diclofenac
Chlorzoxazone + Diclofenac
🏭 Manufacturer
Affy Pharma Pvt Ltd
Affy Pharma Pvt Ltd
📦 Form
Allopathy
Allopathy
🤰 Pregnancy Category
Category A
Category A
🇮🇳 ache x tablet के बारे में संक्षिप्त जानकारी
ache x tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Chlorzoxazone (250mg) + Diclofenac (50mg) मौजूद है।
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.
📋 Complete Drug Information
| Generic Name(s) | Chlorzoxazone + Diclofenac |
|---|---|
| Brand Name | Ache X Tablet |
| Manufacturer | Affy Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Muscle Relaxant + NSAID |
| Route of Administration | Oral |
| Storage | Store at 20-25°C, protect from moisture |
🔬 Pharmacology
Pharmacokinetics
AbsorptionWell absorbed orally
DistributionDistributes widely; crosses placenta
Protein BindingChlorzoxazone: 13-18%; Diclofenac: >99%
MetabolismChlorzoxazone: Hepatic (CYP2E1); Diclofenac: Hepatic (CYP2C9)
Half-LifeChlorzoxazone: 1-2 hrs; Diclofenac: 2 hrs
ExcretionUrine (metabolites)
BioavailabilityChlorzoxazone: ~100%; Diclofenac: ~50%
Onset of Action30-60 minutes
Peak Plasma Time1-2 hours
Duration of Action4-6 hours
Mechanism of Action
Chlorzoxazone: Depresses CNS; Diclofenac: Inhibits COX-1/2
Step-by-Step Mechanism
1
Chlorzoxazone acts on CNS to depress reflexes and relax muscles
2
Diclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes
3
COX inhibition reduces prostaglandin synthesis
4
Decreased prostaglandins lead to reduced pain and inflammation
💡 How to take ache x tablet
Prescribed Dosage: Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose.
- ✅ Complete the full course of medication.
- ✅ Store at 20-25°C, protect from moisture
⚠️ Side Effects of ache x tablet
✅ Common Side Effects
- Drowsiness
- Dizziness
- Nausea
- Dyspepsia
- Headache
🚨 Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Anaphylaxis
⚠️ Rare Side Effects
- Blood dyscrasias
- Stevens-Johnson syndrome
- Pancreatitis
Important: Consult your doctor if you experience any unusual symptoms or severe side effects.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased GI ulceration risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| CYP2C9 inhibitors | Major | Increased diclofenac levels |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased GI ulceration risk |
| Antacids | Minor | Reduced absorption |
| Caffeine | Minor | Increased CNS stimulation |
🚨 Major Interactions
- Warfarin
- Aspirin
- Lithium
- Methotrexate
- CYP2C9 inhibitors
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
🍽️ Food Interactions
Food may delay absorption
🍷 Alcohol Interaction
Increased hepatotoxicity risk
🛡️ Safety & Warnings
Pregnancy
Category A
Liver Risk
Low
Kidney Risk
Low
Heart Risk
Low
🚫 Contraindications
Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, history of asthma with NSAIDs, third trimester pregnancy
📊 Monitoring Parameters
Liver function, renal function, CBC, signs of GI bleeding
🤱 Lactation Safety
Not recommended; excreted in milk
💊 Overdose
Symptomatic and supportive; gastric lavage, activated charcoal
⏰ Missed Dose
Take as soon as remembered; skip if near next dose