acetus-s tablet allopathy (Aceclofenac (100mg) + Paracetamol (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
acetus-s tablet allopathy (Aceclofenac (100mg) + Paracetamol (500mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Radius Healthcare Pvt Ltd. Contains Aceclofenac (100mg) + Paracetamol (500mg).

acetus-s tablet - Uses, Price, Side Effects & Substitutes

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🏭 Radius Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is acetus-s tablet used for?

Aldigesic P (Aceclofenac + Paracetamol) is used to treat Pain and inflammation in osteoarthritis. It contains Aceclofenac (100mg) + Paracetamol (500mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Radius Healthcare Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 acetus-s tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

acetus-s tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerRadius Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

💡 How and when to take acetus-s tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How acetus-s tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 acetus-s tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of acetus-s tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for acetus-s tablet

View All

Alternative medicines with exact same composition and strength (Aceclofenac (100mg) + Paracetamol (500mg)):

  1. acuflam sp 100 mg/500 mg/15 mg tablet
    Alkem Laboratories Ltd₹5.79💰 90.8% CHEAPER
  2. acefinac sp tablet
    Ortin Laboratories Ltd₹7.03💰 88.8% CHEAPER
  3. unigesic plus tablet
    Torrent Pharmaceuticals Ltd₹7.50💰 88.1% CHEAPER
  4. aceclomac plus 100 mg/500 mg tablet
    Torque Pharmaceuticals Pvt Ltd₹8.67💰 86.2% CHEAPER
  5. elzefen p tablet
    Elder Pharmaceuticals Ltd₹9.81💰 84.4% CHEAPER
  6. asiflexp 100 mg/500 mg tablet
    Nippon Seiyaku Pvt Ltd₹10.00💰 84.1% CHEAPER
  7. recomol a 100mg/500mg tablet
    Reco Drugs₹10.00💰 84.1% CHEAPER
  8. aclofen plus tablet
    Ind Swift Laboratories Ltd₹10.31💰 83.6% CHEAPER
  9. aceforce p 100 mg/500 mg tablet
    Shreya Life Sciences Pvt Ltd₹10.31💰 83.6% CHEAPER
  10. saclo sp 100mg/500mg/15mg tablet
    Sparkle Life Sciences Pvt Ltd₹13.00💰 79.4% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Aspirin Major Increased risk of GI ulceration
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic efficacy
Anticoagulants Moderate Increased INR
SSRIs Moderate Increased bleeding risk
Antacids Minor Reduced absorption of aceclofenac
Cholestyramine Minor Reduced absorption of paracetamol

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about acetus-s tablet

  • Myth: Generic substitutes of acetus-s tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (500mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of acetus-s tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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