SaathiMed
Diagnose Smarter. Treat Faster.
👨‍⚕️ For Doctors 📱 Download App
🏠 Home > 💊 All Medicines > aceflex plus 100mg/325mg tablet
aceflex plus 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India
aceflex plus 100mg/325mg tablet allopathy (Aceclofenac (100mg) + Paracetamol (325mg)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Cipla Ltd. Contains Aceclofenac (100mg) + Paracetamol (325mg).

aceflex plus 100mg/325mg tablet - Uses, Price, Side Effects & Substitutes

No reviews yet
⬆️ Click any salt to see similar medicines
🏭 Cipla Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is aceflex plus 100mg/325mg tablet used for?

Aldigesic P (Aceclofenac + Paracetamol) is used to treat Pain and inflammation in osteoarthritis. It contains Aceclofenac (100mg) + Paracetamol (325mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Paracetamol
  • Manufacturer: Cipla Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 aceflex plus 100mg/325mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)

aceflex plus 100mg/325mg tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

📋 Drug Information

Generic Name(s)Aceclofenac + Paracetamol
Brand NameAldigesic P
ManufacturerCipla Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%; Paracetamol: 10-25%
MetabolismAceclofenac: hepatic via CYP2C9; Paracetamol: hepatic via glucuronidation and sulfation
Half-LifeAceclofenac: 4-5 h; Paracetamol: 2-3 h
ExcretionRenal (primarily urine)
BioavailabilityAceclofenac: ~100%; Paracetamol: ~88%
Onset of Action30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 h; Paracetamol: 0.5-2 h
Duration of Action4-6 hours

Pharmacodynamics

Mechanism of ActionAceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
Target ReceptorCyclooxygenase (COX) enzymes
Pharmacodynamic EffectsAnalgesic, anti-inflammatory, antipyretic

💡 How and when to take aceflex plus 100mg/325mg tablet?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at room temperature (20-25°C), protect from moisture.

⚙️ How aceflex plus 100mg/325mg tablet Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.

1 Aceclofenac inhibits COX-1 and COX-2, decreasing prostaglandin synthesis.
⬇️
2 Reduced prostaglandins lead to decreased inflammation and pain.
⬇️
3 Paracetamol inhibits COX in the CNS, reducing pain signal transmission.
⬇️
4 Paracetamol acts on hypothalamic heat-regulating center to reduce fever.
⬇️
5 Combined effect provides enhanced analgesia and antipyresis.

💊 aceflex plus 100mg/325mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications

Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.

Off-label uses: Postoperative pain, migraine (limited evidence).

⚠️ What are the side effects of aceflex plus 100mg/325mg tablet?

✅ Common Side Effects

  • Nausea
  • Dizziness
  • Drowsiness
  • Rash
  • GI upset

🚨 Serious Side Effects

  • GI bleeding
  • Hepatotoxicity
  • Renal failure
  • Stevens-Johnson syndrome

⚠️ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

🔄 Best Substitutes for aceflex plus 100mg/325mg tablet

View All

Alternative medicines with exact same composition and strength (Aceclofenac (100mg) + Paracetamol (325mg)):

  1. rumatab sp 100 mg/325 mg/15 mg tablet
    Simpson Brawn Pharmaceuticals₹5.23💰 90.7% CHEAPER
  2. aclopen plus 100mg/325mg tablet
    Morepen Laboratories Ltd₹6.44💰 88.5% CHEAPER
  3. dolospark 100mg/325mg tablet
    Spark Medicare Pvt Ltd₹7.31💰 86.9% CHEAPER
  4. aceforce mr 100 mg/325 mg/250 mg tablet
    Shreya Life Sciences Pvt Ltd₹10.55💰 81.2% CHEAPER
  5. asozen-plus tablet
    Zeelab Pharmacy Pvt Ltd₹11.00💰 80.4% CHEAPER
  6. acefex p 100mg/325mg tablet
    Zydus Cadila₹11.25💰 79.9% CHEAPER
  7. afecox 100 mg/325 mg tablet
    Apostle Remedies₹12.19💰 78.2% CHEAPER
  8. aceclofast tablet
    Wings Biotech Ltd₹12.90💰 77% CHEAPER
  9. dolospark-sp tablet
    Spark Medicare Pvt Ltd₹13.13💰 76.6% CHEAPER
  10. nicoace mr tablet
    Abbott₹15.00💰 73.2% CHEAPER

Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Aspirin Major Increased risk of GI ulceration
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic efficacy
Anticoagulants Moderate Increased INR
SSRIs Moderate Increased bleeding risk
Antacids Minor Reduced absorption of aceclofenac
Cholestyramine Minor Reduced absorption of paracetamol

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • SSRIs

ℹ️ Minor Interactions

  • Antacids
  • Cholestyramine

🍽️ Food Interactions

Food may delay absorption; avoid alcohol.

🍷 Alcohol Interaction

Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

📊 Monitoring Parameters

Liver function tests, renal function, CBC, blood pressure.

🤱 Lactation Safety

Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.

💊 Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

🛑 Myths vs. Facts about aceflex plus 100mg/325mg tablet

  • Myth: Generic substitutes of aceflex plus 100mg/325mg tablet are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of aceflex plus 100mg/325mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

Join Community

Read real stories and discussions from our patient community regarding similar health conditions.

Cystic acne ko hide kaise karein? Foundation se plaster nahi dikhna 😩 Help!

ok so today i had to go to my cousin's wedding and obv i wanted to look decent but my skin is having the worsttt breakout ever. cystic acne on my jawline and cheeks, like those big painful bumps that take forever to go. i tried concealer but it just looked cakey and gross. plus my mom was like "beta face pe kya laga rakha hai, zyada makeup mat karo, daag ho jayenge" like ma'am the daag are already there thanks to my pimple popping addiction 😭 so i ended up using this green color corrector i got from nykaa, then layered a full coverage foundation (the loreal one in the tube) and set it with loose powder. it kinda worked? but after 2 hours it started creasing around my nose and the acne bumps were still visible through it. like you could see the texture. so embarrassing. anyone have tips for hiding cystic acne without looking like a plastered wall? i need something that stays matte and doesn't settle into the bumps. also pls recommend a good primer that blurs pores. i'm so tired of relatives giving me unsolicited advice about besan and haldi face packs 😩 help a sister out

Indian Doctor’s Guide to Intermittent Fasting for Weight Loss

Intermittent Fasting (IF) is rapidly gaining popularity worldwide, and for good reason. As an Indian doctor, I often see patients struggling with weight gain, insulin resistance, and digestive issues—all of which can be effectively managed with a well-planned IF routine. But the key word here is Indian. Our traditional diet, rich in carbohydrates and spices, requires a tailored approach. Let me guide you through a complete, medically accurate plan that respects your body and your lifestyle. Why Intermittent Fasting Works for Indians Our bodies, especially in the Indian context, are often conditioned to eat throughout the day—chai, snacks, and heavy meals. This constant eating keeps insulin levels high, leading to fat storage and metabolic sluggishness. IF gives your digestive system a break, allowing insulin levels to drop and your body to burn stored fat for energy. It also improves gut health, reduces inflammation, and can even enhance mental clarity. But remember, it’s not about starving; it’s about timing your meals wisely. Best Intermittent Fasting Timings for Indians For most Indians, the 16:8 method is the most practical and sustainable. This means you fast for 16 hours and eat within an 8-hour window. Here’s a realistic schedule that fits our daily rhythm: Fasting Window: 8 PM to 12 PM (next day). This aligns with our dinner time and skips breakfast, which many of us already do. Eating Window: 12 PM to 8 PM. You have lunch, an afternoon snack, and dinner. Alternatively, if you are a morning person, try 14:10 (fast 14 hours, eat in 10 hours) starting from 7 PM to 9 AM. This is gentler for beginners or those with high physical activity. Complete Daily Routine for an Indian IF Practitioner Here’s a step-by-step routine that respects your body’s natural cycles: Morning (6 AM - 12 PM): Fasting Phase – Drink plenty of water, black tea, or green tea. Avoid milk, sugar, or any calories. You can have lemon water with a pinch of black salt to replenish electrolytes. This is the time for light exercise like yoga or walking. Lunch (12 PM - 1 PM): Break Your Fast – Start with a balanced meal: dal, roti, sabzi, and a small bowl of curd. Avoid fried foods or heavy sweets. This meal should be your largest of the day. Afternoon Snack (4 PM - 5 PM) – A handful of nuts (almonds, walnuts) or a fruit like an apple. Avoid packaged snacks or chips. This keeps your energy stable. Dinner (7 PM - 8 PM) – Keep it light and early. Think khichdi, soup, or grilled paneer with salad. Avoid heavy curries, rice, or rotis at night. Finish eating by 8 PM sharp. What to Eat and Avoid During Your Eating Window To maximize benefits, focus on whole, unprocessed foods. Here’s a quick guide: Eat: Lentils (dal), chickpeas (chana), green vegetables, whole grains (bajra, jowar, brown rice), eggs, paneer, nuts, seeds, and ghee in moderation. Avoid: Refined flour (maida), sugary drinks, packaged namkeen, fried samosas, and excessive sweets. These spike insulin and break your fast’s benefits. When to See a Doctor Intermittent Fasting is not for everyone. Please consult your doctor before starting if you have: Diabetes (especially on insulin or sulfonylureas) Low blood pressure or a history of fainting Eating disorders (anorexia, bulimia) Pregnancy, breastfeeding, or trying to conceive Chronic kidney or liver disease If you experience severe dizziness, persistent headaches, or rapid weight loss, stop immediately and seek medical advice. Your health is your greatest wealth—listen to your body.

Wake up tired? Your thyroid might be the culprit

If you wake up feeling like a heavy stone is sitting on your chest, or if your limbs feel like lead even after a full night's sleep, you are not alone. As an Indian doctor, I see countless patients, especially women, who struggle with this invisible weight. The culprit is often our own thyroid gland—specifically, hypothyroidism. When your thyroid is underactive, your metabolism slows down to a crawl, leading to extreme fatigue that no amount of chai or coffee can fix. Let’s understand why this happens and, more importantly, how you can reclaim your energy. Why Does Hypothyroidism Drain Your Energy? Your thyroid gland produces hormones (T3 and T4) that act like the accelerator pedal for your body’s engine. In hypothyroidism, your body doesn’t make enough of these hormones. This slows down every process, from your heart rate to your digestion. The result is a deep, bone-tired fatigue that doesn’t go away with rest. You might also notice weight gain, feeling cold when others are warm, dry skin, constipation, and a foggy brain. This is your body’s way of saying, “My fuel is low, and I need help.” Actionable Home Remedies & Diet Tips to Boost Energy and Metabolism While your doctor will prescribe Thyroxine (levothyroxine) to replace the missing hormone, what you eat and do at home makes a huge difference. Here are my top recommendations for my Indian patients: 1. The Golden Rule: Take Your Medicine Correctly Empty stomach, first thing in the morning: Take your tablet with only plain water, at least 30-60 minutes before any food or other medicines. Avoid these for 4 hours: Calcium (milk, curd, paneer), iron (chana, leafy greens), and high-fiber foods (chokha, whole grains). They block absorption. 2. Eat for Your Thyroid (Desi Style) Go for Selenium-rich foods: Selenium helps convert T4 to the active T3. Eat 1-2 Brazil nuts daily, or include mushrooms, sunflower seeds, and eggs. Zinc is your friend: Pumpkin seeds, chana, and rajma are excellent sources of zinc, which supports thyroid function. Iodine – but carefully: Use iodized salt in your dal or sabzi, but don’t overdo it. Avoid eating raw cruciferous veggies (like cabbage, cauliflower, broccoli) in large amounts, as they can interfere with thyroid function. Cooking them neutralizes this effect. Protein is a must: Include dal, sprouts, eggs, fish, or chicken in every meal. Protein helps transport thyroid hormones in the blood. 3. Simple Lifestyle Hacks for More Energy Start slow, but move: Don’t aim for a marathon. A 15-minute walk after breakfast or a gentle yoga session (Surya Namaskar, but slowly) can stimulate metabolism without exhausting you. Manage stress: High stress raises cortisol, which blocks thyroid function. Try 5 minutes of deep breathing (pranayama) daily. Sleep hygiene: Go to bed at the same time. Avoid phone screens 30 minutes before sleep. A dark, cool room helps your body reset. When to See a Doctor Immediately Home remedies are supportive, but they are not a replacement for medical care. You must see your doctor if: Your fatigue becomes so severe that you cannot get out of bed or do basic chores. You experience chest pain, shortness of breath, or a very slow heart rate (below 60 beats per minute). You notice swelling in your neck (goiter) or puffiness around your eyes. You feel depressed, confused, or have memory problems that affect your work or family life. Your weight continues to increase despite eating well and exercising. Remember: Hypothyroidism is a chronic condition, but with the right medicine, diet, and lifestyle, you can live a full, energetic life. You are not lazy; your body is struggling. Be kind to yourself, follow your doctor’s advice, and take one small step each day. Your energy will return.

Browse SaathiMed's Medicines A-Z

Search our extensive medical database alphabetically to find uses, price, composition, and side effects.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install