acefenac sp tablet - Uses, Price, Side Effects & Substitutes
What is acefenac sp tablet used for?
Adiflam Plus 400 mg/500 mg Tablet (Ibuprofen + Paracetamol) is used to treat Mild to moderate pain. It contains Ibuprofen (100mg) + Paracetamol (15mg), which Ibuprofen inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamo. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ibuprofen + Paracetamol
- Manufacturer: Medichem Pharmceuticals Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 acefenac sp tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
acefenac sp tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Ibuprofen (100mg) + Paracetamol (15mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Ibuprofen + Paracetamol |
|---|---|
| Brand Name | Adiflam Plus 400 mg/500 mg Tablet |
| Manufacturer | Medichem Pharmceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take acefenac sp tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from moisture.
⚙️ How acefenac sp tablet Works
Ibuprofen inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in CNS, reducing pain and fever.
💊 acefenac sp tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Mild to moderate pain, fever, inflammation (e.g., headache, dental pain, dysmenorrhea, osteoarthritis).
Off-label uses: Patent ductus arteriosus closure (ibuprofen), migraine (paracetamol).
⚠️ What are the side effects of acefenac sp tablet?
✅ Common Side Effects
- Nausea
- Dyspepsia
- Headache
- Dizziness
- Rash
🚨 Serious Side Effects
- GI bleeding
- Renal failure
- Hepatotoxicity
- Cardiovascular events
- Stevens-Johnson syndrome
⚠️ Rare Side Effects
- Aplastic anemia
- Agranulocytosis
- Pancreatitis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased GI bleeding risk |
| Other NSAIDs | Major | Additive GI and renal toxicity |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased GI ulcer risk |
| Antacids | Minor | Reduced absorption of ibuprofen |
| Caffeine | Minor | Additive analgesic effect |
| Cholestyramine | Minor | Reduced absorption of paracetamol |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Other NSAIDs
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
ℹ️ Minor Interactions
- Antacids
- Caffeine
- Cholestyramine
🍽️ Food Interactions
Food may delay absorption; avoid high-fat meals.
🍷 Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, active GI bleeding, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs.
📊 Monitoring Parameters
Renal function, hepatic function, blood pressure, signs of GI bleeding.
🤱 Lactation Safety
Ibuprofen: Safe in low doses; Paracetamol: Safe.
💊 Overdose Management
Activated charcoal, supportive care; for paracetamol overdose: N-acetylcysteine.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose.
🛑 Myths vs. Facts about acefenac sp tablet
- Myth: Generic substitutes of acefenac sp tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Ibuprofen (100mg) + Paracetamol (15mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of acefenac sp tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
💬 Real Patient Experiences (Astitva)
Join CommunityRead real stories and discussions from our patient community regarding similar health conditions.