acefe-p tablet - Uses, Price, Side Effects & Substitutes
What is acefe-p tablet used for?
Aldigesic P (Aceclofenac + Paracetamol) is used to treat Pain and inflammation in osteoarthritis. It contains Aceclofenac (100mg) + Paracetamol (325mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paraceta. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Asterisk Laboratories India Pvt Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 acefe-p tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
acefe-p tablet का उपयोग मुख्य रूप से pain analgesics और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Aceclofenac (100mg) + Paracetamol (325mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
|---|---|
| Brand Name | Aldigesic P |
| Manufacturer | Asterisk Laboratories India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take acefe-p tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from moisture.
⚙️ How acefe-p tablet Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, elevating pain threshold and acting on hypothalamic heat-regulating center.
💊 acefe-p tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, dysmenorrhea, fever.
Off-label uses: Postoperative pain, migraine (limited evidence).
⚠️ What are the side effects of acefe-p tablet?
✅ Common Side Effects
- Nausea
- Dizziness
- Drowsiness
- Rash
- GI upset
🚨 Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Stevens-Johnson syndrome
⚠️ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased risk of GI ulceration |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic efficacy |
| Anticoagulants | Moderate | Increased INR |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of aceclofenac |
| Cholestyramine | Minor | Reduced absorption of paracetamol |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
⚡ Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- SSRIs
ℹ️ Minor Interactions
- Antacids
- Cholestyramine
🍽️ Food Interactions
Food may delay absorption; avoid alcohol.
🍷 Alcohol Interaction
Increased risk of hepatotoxicity (paracetamol) and GI bleeding (aceclofenac).
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.
📊 Monitoring Parameters
Liver function tests, renal function, CBC, blood pressure.
🤱 Lactation Safety
Caution; paracetamol is safe, aceclofenac may be excreted in small amounts.
💊 Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care for aceclofenac.
⏰ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.
🛑 Myths vs. Facts about acefe-p tablet
- Myth: Generic substitutes of acefe-p tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Aceclofenac (100mg) + Paracetamol (325mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of acefe-p tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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