acedrot 80mg/100mg tablet - Uses, Price, Side Effects & Substitutes
What is acedrot 80mg/100mg tablet used for?
Aceclo Spas Tablet (Drotaverine + Aceclofenac) is used to treat GASTRO INTESTINAL. It contains Drotaverine (80mg) + Aceclofenac (100mg), which Drotaverine inhibits phosphodiesterase-4, increasing cAMP, leading to smooth mus. Always consult your doctor before use. Take as prescribed.
- Generic Name: Drotaverine + Aceclofenac
- Manufacturer: Newgen Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acedrot 80mg/100mg tablet Uses & Benefits
Treatment of smooth muscle spasms associated with pain, such as in gastrointestinal, biliary, and renal colic
Off-label uses: Dysmenorrhea, musculoskeletal pain
๐ Drug Information
| Generic Name(s) | Drotaverine + Aceclofenac |
| Brand Name | Aceclo Spas Tablet |
| Manufacturer | Newgen Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Drotaverine inhibits phosphodiesterase-4, increasing cAMP, leading to smooth muscle relaxation. Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take acedrot 80mg/100mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acedrot 80mg/100mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Dizziness
- Headache
- Abdominal pain
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Stevens-Johnson syndrome
- Agranulocytosis
- Pancreatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Methotrexate | Major | Increased methotrexate toxicity |
| Lithium | Major | Increased lithium levels |
| Aspirin | Major | Increased GI ulceration risk |
| Other NSAIDs | Major | Additive GI toxicity |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased GI ulceration risk |
| Antacids | Minor | Reduced absorption of aceclofenac |
| Cholestyramine | Minor | Reduced absorption of aceclofenac |
๐จ Major Interactions
- Warfarin
- Methotrexate
- Lithium
- Aspirin
- Other NSAIDs
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Anticoagulants
- Corticosteroids
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
May be taken with food to reduce GI upset
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs
๐ Monitoring Parameters
Liver function, renal function, blood pressure, signs of GI bleeding
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage if recent ingestion
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose